Does Poly-Vi-Sol (multivitamin supplement) contain iron, particularly for pediatric patients?

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Does Poly-Vi-Sol Contain Iron?

Poly-Vi-Sol is available in two formulations: one WITHOUT iron and one WITH iron (Poly-Vi-Sol with Iron). The standard Poly-Vi-Sol multivitamin drops do not contain iron, but parents and clinicians must specifically select the "with iron" formulation if iron supplementation is desired 1.

Key Formulation Details

The iron-containing version (Poly-Vi-Sol with Iron) provides approximately 10 mg of elemental iron per 1 mL dose, which is the typical daily serving for infants and young children 1, 2. This amount is designed to meet the recommended dietary allowance for iron in healthy infants but falls below therapeutic dosing for iron-deficiency anemia 3.

Clinical Context for Iron Supplementation

  • For prevention of iron deficiency in healthy infants: Iron-fortified formulas and multivitamins containing iron (like Poly-Vi-Sol with Iron) provide sufficient iron to meet nutritional needs 1

  • For treatment of confirmed iron-deficiency anemia: The standard therapeutic dose is 3 mg/kg per day of elemental iron given as ferrous sulfate drops between meals, which typically exceeds what multivitamin preparations provide 3

  • Breast-fed infants starting at 4 months: Introduction of iron-fortified cereals or supplements protects against iron deficiency, with only 3% developing iron-deficiency anemia compared to 15% receiving non-iron-fortified options 1

Important Prescribing Considerations

Always verify the specific product label, as children's multivitamin preparations vary widely in iron content 2. Approximately 44% of children's multivitamin products contain iron, while 56% do not 4.

Safety Profile

  • Accidental ingestions of children's multivitamins with iron rarely cause significant toxicity when the product is the child's own dietary supplement 4

  • The mean iron ingestion in pediatric overdose cases was 16.8 mg/kg, with 100% of patients showing no significant toxic effects when promptly managed 4

  • Iron from chewable multivitamins is well absorbed and potentially comparable to iron tablets, though severe poisonings from multivitamins remain uncommon in clinical practice 5

When Multivitamins Are Insufficient

If treating confirmed iron-deficiency anemia, prescribe dedicated iron supplementation rather than relying on multivitamin formulations 3. The 10 mg of iron in typical pediatric multivitamins cannot deliver the 3 mg/kg per day needed for therapeutic correction of anemia in most children over 3-4 kg body weight 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Characteristics of vitamin and mineral supplement products in the United States.

The American journal of clinical nutrition, 1991

Guideline

Iron Supplementation for Treatment of Iron-Deficiency Anemia in Infants

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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