Essential Guide for First-Year Family Medicine Residents in the Emergency Department
Most Common ED Presentations You Will Encounter
As a first-year family medicine resident, you will primarily manage psychiatric emergencies, stroke presentations, trauma (especially falls in elderly patients), respiratory emergencies, and acute behavioral crises. 1
1. Psychiatric and Behavioral Emergencies (≈6% of all ED visits)
Initial Assessment Approach
For alert, cooperative psychiatric patients with normal vital signs and non-contributory history/physical exam, routine laboratory testing is NOT necessary and should be avoided. 1
- Medical clearance labs are low-yield: Only 1.2% of routine testing in psychiatric patients yields clinically significant findings that change management 1
- Order labs ONLY when history or physical exam suggests medical cause: altered mental status, abnormal vital signs, new-onset psychiatric symptoms, or specific clinical suspicion 1
- Urine drug screens rarely change ED management: Multiple studies show no significant difference in disposition between positive and negative screens 1
Critical Medical Mimics to Rule Out
Before accepting a psychiatric diagnosis, actively exclude these conditions through targeted history and exam 1:
Metabolic/Endocrine:
- Hypoglycemia, hyperglycemia, hyponatremia, hypocalcemia
- Thyroid disease (hyperthyroidism, thyroid storm, hypothyroidism)
- Uremia, hyperammonemia
Neurologic:
- Seizures, stroke, intracranial hemorrhage
- Encephalitis, meningitis
- Brain tumors (rare but can present with psychiatric symptoms)
Toxicologic:
- Drug withdrawal: alcohol, benzodiazepines, barbiturates
- Drug intoxication: cocaine, amphetamines, PCP, bath salts, synthetic cannabinoids
- Medication effects: steroids, anticholinergics, psychiatric medications
Other:
- Hypoxia, hypercarbia
- Carbon monoxide poisoning
- Infections (especially in young children and elderly)
Suicidal Ideation/Attempt Management
Suicide is the 3rd leading cause of death in ages 10-24 years, accounting for >4000 deaths annually; females attempt more but males complete suicide 5× more often due to more lethal means. 1
High-risk factors requiring psychiatric consultation: 1
- Previous psychiatric disorder or recent hospitalization
- Substance abuse
- Family history of suicide
- History of sexual/physical abuse
- Homeless/runaway status
- LGBTQ+ identification
- Recent psychosocial stressors (family conflict, relationship breakup, bullying, legal troubles)
Immediate safety measures: 1
- Personal and belongings search
- Change into hospital attire
- Place in safe room without access to medical equipment
- Close staff supervision
- Interview patient and caregivers separately
- Obtain collateral information (patients often minimize severity)
Acute Agitation Management
For the acutely agitated patient, pharmacologic treatment is indicated when verbal de-escalation fails. 1
First-line options (choose based on clinical scenario):
- Haloperidol 5 mg IM (typical antipsychotic)
- Olanzapine 10 mg IM (atypical antipsychotic, less extrapyramidal symptoms)
- Lorazepam 2 mg IM (benzodiazepine, useful if alcohol withdrawal suspected)
- Combination: Haloperidol 5 mg + Lorazepam 2 mg IM (synergistic effect)
Critical pitfall: Avoid diphenhydramine in geriatric patients—it's a high-risk medication in this population 1
2. Acute Stroke (Time-Critical Emergency)
Immediate Actions (First 10 Minutes)
Your primary goal is door-to-needle time ≤60 minutes for thrombolysis candidates; every minute of delay worsens outcomes. 2, 3
Simultaneous initial steps: 2
- Stabilize ABCs: Supplemental O₂ if SpO₂ <94%
- Establish IV access immediately
- Obtain blood samples: CBC, coagulation studies (PT/INR/PTT), platelets, electrolytes, renal function, glucose, cardiac troponin
- Labs must be available within 20 minutes for thrombolysis candidates
- Order non-contrast head CT STAT (target: completion within 30 minutes of arrival)
- Check blood glucose at bedside (hypoglycemia mimics stroke)
- Assess with NIHSS (National Institutes of Health Stroke Scale)
Blood Pressure Management (Critical for Thrombolysis Eligibility)
BP must be <185/110 mmHg BEFORE tPA and maintained <180/105 mmHg during and for 24 hours after treatment. 2, 3
For BP >185/110 mmHg in thrombolysis candidates: 2
- Labetalol 10-20 mg IV over 1-2 minutes, may repeat once, OR
- Nicardipine IV 5 mg/hr, titrate up by 2.5 mg/hr every 5-15 minutes (maximum 15 mg/hr)
For non-thrombolysis candidates: 3
- Do NOT treat BP unless systolic >220 mmHg or diastolic >120 mmHg
- Exception: Intracerebral hemorrhage with hypertension history—keep MAP <130 mmHg
Thrombolytic Therapy
Alteplase (tPA) 0.9 mg/kg IV (maximum 90 mg total dose) is indicated for eligible patients within 4.5 hours of symptom onset. 2, 3
Dosing:
- 10% as IV bolus over 1 minute
- Remaining 90% as IV infusion over 60 minutes
Absolute contraindications:
- Intracranial hemorrhage on CT
- BP >185/110 mmHg despite treatment
- Recent surgery/trauma
- Active bleeding
- Platelets <100,000
Continuous Monitoring Post-Stroke
All stroke patients require: 2
- Continuous automated monitoring: SpO₂, BP, cardiac rhythm, temperature
- Cardiac monitoring ×24 hours minimum (detect atrial fibrillation)
- Temperature checks every 4 hours ×48 hours
- Frequent NIHSS assessments to detect complications
DVT Prophylaxis (Start Immediately)
Apply intermittent pneumatic compression (IPC) devices to all immobilized patients immediately; continue until independently mobile or 30 days. 2
Pharmacologic prophylaxis for high-risk patients: 2
- Enoxaparin (low-molecular-weight heparin) for most patients
- Unfractionated heparin for renal failure patients
Critical pitfall: Never use anti-embolism stockings alone—they are ineffective without IPC or pharmacologic prophylaxis 2
3. Geriatric Emergencies (Falls, Polypharmacy, Delirium)
Medication Reconciliation (Mandatory for ALL Geriatric Patients)
Every geriatric patient requires immediate comprehensive medication reconciliation regardless of presenting complaint; 40% take 5-9 medications daily, 18% take >10 medications. 1, 4
Why this matters: 1
- 50-60% chance of drug-drug interaction with 5 medications
- 90% chance of drug-drug interaction with ≥10 medications
- Adverse drug events are a major cause of ED visits and admissions
Obtain medication list from: 4
- Patient
- Caregivers/family
- Skilled nursing facility staff
- Electronic medical records
High-Risk Medications in Geriatrics (Screen Every Patient)
Patients with polypharmacy (>5 medications) or high-risk medications require pharmacist consultation before admission. 1, 4
Common high-risk medications to identify:
- Diphenhydramine (Benadryl)—avoid in elderly 1
- Benzodiazepines
- Anticholinergics
- NSAIDs
- Opioids
- Sliding-scale insulin
Trauma in Elderly (Even Minor Falls Are High-Risk)
Falls represent major traumatic mechanisms in geriatric patients and cause disproportionate morbidity/mortality compared to younger patients. 1
Lower threshold for imaging:
- Head CT for any head strike (even without loss of consciousness)
- C-spine imaging for neck pain or tenderness
- Consider occult fractures (hip, pelvis, vertebral compression)
Why elderly are high-risk: 1
- Anticoagulation use common
- Osteoporosis
- Polypharmacy affecting balance
- Baseline frailty
4. Respiratory Emergencies
Initial Assessment and Treatment
Respiratory emergencies are among the most common office/ED emergencies requiring immediate intervention. 1, 5
Immediate actions:
- Pulse oximetry
- Supplemental O₂ to maintain SpO₂ >94%
- Assess work of breathing, respiratory rate, accessory muscle use
- Auscultate lungs
Common presentations:
- Asthma exacerbation
- COPD exacerbation
- Pneumonia
- Pulmonary embolism
- Anaphylaxis
For asthma/COPD exacerbation:
- Albuterol 2.5-5 mg nebulized (can repeat every 20 minutes ×3)
- Ipratropium 0.5 mg nebulized (add to albuterol)
- Prednisone 40-60 mg PO or methylprednisolone 125 mg IV
- Consider magnesium sulfate 2 g IV over 20 minutes for severe exacerbations
5. Seizures
Acute Management
Clinical seizures require immediate antiseizure medication; patients with altered mental status and electrographic seizures on EEG also require treatment. 1
First-line treatment:
- Lorazepam 0.1 mg/kg IV (usual adult dose 4 mg IV), may repeat once after 5-10 minutes, OR
- Diazepam 0.15 mg/kg IV (usual adult dose 10 mg IV)
If IV access unavailable:
- Midazolam 10 mg IM (for adults)
Second-line (if seizures continue):
- Fosphenytoin 20 mg PE/kg IV at 100-150 mg PE/min
- Levetiracetam 60 mg/kg IV (maximum 4500 mg)
Critical pitfall: Do NOT start long-term anticonvulsants for single self-limiting seizures 2
6. Chest Pain/Acute Coronary Syndrome
Immediate Workup
Every chest pain patient requires:
- 12-lead ECG within 10 minutes of arrival
- Cardiac troponin (baseline and serial)
- Aspirin 162-325 mg PO (chewed) unless contraindicated
- IV access
- Continuous cardiac monitoring
- Supplemental O₂ if SpO₂ <94%
For STEMI:
- Activate cath lab immediately
- Aspirin 325 mg PO
- Ticagrelor 180 mg PO or clopidogrel 600 mg PO
- Heparin bolus 60 units/kg IV (max 4000 units), then infusion
- Nitroglycerin 0.4 mg SL every 5 minutes ×3 for chest pain
- Morphine 2-4 mg IV for persistent pain (use cautiously—associated with increased mortality in NSTEMI) 3
7. Hypoglycemia
Recognition and Treatment
Check blood glucose in ANY patient with altered mental status, confusion, or stroke-like symptoms—hypoglycemia mimics many conditions. 2, 3
Treatment for glucose <70 mg/dL with symptoms:
- If conscious and able to swallow: 15-20 g oral glucose (juice, glucose tablets)
- If altered or unable to swallow: Dextrose 50% 25 g (50 mL) IV push
- If no IV access: Glucagon 1 mg IM
Recheck glucose in 15 minutes and repeat treatment if needed
8. Anaphylaxis
Immediate Treatment
Anaphylaxis is a clinical diagnosis requiring immediate epinephrine—do not delay for labs or testing. 1
First-line treatment:
- Epinephrine 0.3-0.5 mg IM (1:1000 concentration) into anterolateral thigh
- May repeat every 5-15 minutes if needed
Adjunctive treatments:
- Diphenhydramine 50 mg IV/IM (H1 blocker)
- Ranitidine 50 mg IV or famotidine 20 mg IV (H2 blocker)
- Methylprednisolone 125 mg IV (prevent biphasic reaction)
- Albuterol nebulized for bronchospasm
- IV fluid bolus for hypotension
Observe minimum 4-6 hours (biphasic reactions occur in 20%)
Critical Pitfalls to Avoid in the ED
Delaying stroke thrombolysis for non-essential tests (chest X-ray, additional imaging unless specific concerns) 2
Ordering routine labs on psychiatric patients with normal vital signs and exam—this is low-yield and costly 1
Missing medication reconciliation in geriatric patients—adverse drug events are a leading cause of ED visits 1, 4
Treating blood pressure in stroke patients before determining thrombolysis eligibility—you may make them ineligible 2, 3
Using anti-embolism stockings alone for DVT prophylaxis—they are ineffective without IPC or pharmacologic prophylaxis 2
Starting long-term anticonvulsants for single self-limiting seizures 2
Failing to check glucose in altered mental status—hypoglycemia mimics stroke, psychiatric emergencies, and seizures 2, 3
Ordering brain CT on every psychiatric patient—radiation exposure risk outweighs benefit without focal neurologic findings 1
Delaying epinephrine in suspected anaphylaxis—it is the only life-saving treatment 1
Missing suicidal ideation in adolescents—always interview patient and caregivers separately 1