What ICD‑10 code should be used for copper deficiency occurring after a gastric bypass surgery?

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ICD-10 Code for Copper Deficiency After Gastric Bypass Surgery

The appropriate ICD-10 code for copper deficiency occurring after gastric bypass surgery is E61.0 (Copper deficiency), which should be coded alongside Z98.84 (Bariatric surgery status) to capture both the deficiency and its surgical etiology.

Primary Diagnosis Code

  • E61.0 is the specific ICD-10 code for copper deficiency and should be listed as the primary diagnosis when copper deficiency is the reason for the encounter 1, 2, 3, 4

Essential Secondary Code

  • Z98.84 (Bariatric surgery status) must be added as a secondary code to document the underlying cause and surgical history that predisposed the patient to this nutritional deficiency 2, 3, 4, 5

Additional Codes Based on Clinical Manifestations

If the copper deficiency has resulted in specific complications, add the following codes as clinically appropriate:

  • D53.9 (Nutritional anemia, unspecified) or D64.9 (Anemia, unspecified) if anemia is present 2, 3, 4, 6
  • D70.9 (Neutropenia, unspecified) if neutropenia or leukopenia has developed 4, 6
  • D69.6 (Thrombocytopenia, unspecified) if thrombocytopenia is documented 1, 6
  • G95.9 (Disease of spinal cord, unspecified) or G62.9 (Polyneuropathy, unspecified) if myeloneuropathy or peripheral neuropathy is present 1, 2, 3, 4

Clinical Context for Coding Accuracy

Copper deficiency after gastric bypass presents with distinctive features that support accurate diagnosis coding:

  • Hematologic manifestations include anemia, neutropenia, leukopenia, thrombocytopenia, and bone marrow dysplasia that can mimic myelodysplastic syndrome 4, 6
  • Neurologic manifestations include myeloneuropathy with posterior column involvement, peripheral neuropathy, ataxia, and gait abnormalities that may be irreversible if treatment is delayed 2, 3, 4, 5
  • Copper deficiency is particularly common after Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD/DS) procedures due to malabsorption 1, 3, 4

Common Coding Pitfall to Avoid

  • Do not use E83.0 (Disorders of copper metabolism), which is reserved for genetic disorders like Wilson's disease or Menkes disease, not acquired copper deficiency from malabsorption 1, 2
  • Always include Z98.84 to establish the causal relationship between the bariatric surgery and the nutritional deficiency, as this affects treatment planning and monitoring requirements 1, 3

Documentation Requirements

Ensure medical documentation includes:

  • Laboratory confirmation of low serum copper levels (typically <70 µg/dL) and low ceruloplasmin 2, 3, 4
  • Type of bariatric procedure performed (RYGB, sleeve gastrectomy, BPD/DS) 1
  • Time interval since surgery, as copper deficiency typically manifests months to years post-operatively 2, 4, 5
  • Presence or absence of concurrent zinc supplementation, which can precipitate copper deficiency 1, 7, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A Case of Copper Deficiency Myeloneuropathy Precipitated by Zinc Ingestion and Bariatric Surgery.

South Dakota medicine : the journal of the South Dakota State Medical Association, 2020

Research

Clinical Manifestations of Copper Deficiency: A Case Report and Review of the Literature.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2021

Research

Copper deficiency (hypocupremia) and pancytopenia late after gastric bypass surgery.

Proceedings (Baylor University. Medical Center), 2013

Guideline

Zinc and Copper Supplementation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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