From the FDA Drug Label
Take lurasidone hydrochloride tablets by mouth, with food (at least 350 calories) The FDA drug label suggests that taking Lurasidone with food (at least 350 calories) may help minimize nausea associated with therapy 1.
- Key points to minimize nausea:
- Take Lurasidone with food
- Ensure the food intake is at least 350 calories No other direct methods to minimize nausea are mentioned in the label.
From the Research
Minimizing Nausea Associated with Latuda (Lurasidone) Therapy
To minimize nausea associated with Latuda (Lurasidone) therapy, consider the following:
- Take Lurasidone with food, as its bioavailability appears to be increased by food 2, 3, 4
- Be aware that nausea is a common side effect, especially early in treatment, and may decrease over time 2, 5, 3, 4
- The risk of nausea may be lower when taking Lurasidone at a dose of 20-60mg/d compared to 80-120mg/d 6
- Compared to other treatments approved for bipolar depression, Lurasidone may have a lower risk of harm, including nausea 6
Additional Considerations
- Lurasidone may cause other gastrointestinal side effects, such as vomiting 3
- The medication should be taken at night with food, as absorption is halved on an empty stomach 4
- Patients experiencing nausea or other side effects should consult their healthcare provider for guidance on managing these effects 2, 5, 3, 4, 6