What is the treatment for nausea in patients with End-Stage Renal Disease (ESRD)?

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From the Research

Treatment for Nausea in ESRD Patients

  • Nausea is a common symptom in patients with End-Stage Renal Disease (ESRD), affecting their quality of life 1, 2, 3.
  • Several medications can be used to manage nausea in ESRD patients, including:
    • Ondansetron 1
    • Metoclopramide 1
    • Haloperidol 1
  • Mirtazapine, a noradrenergic antagonist and selective serotonin antagonist, has been proposed as a potential one-stop pharmacologic agent to alleviate multiple symptoms, including nausea, in ESRD patients 2.
  • Intradialytic complications, such as nausea and vomiting, can occur during hemodialysis sessions, with a frequency of 11.7% in one study 3.

Management of ESRD Symptoms

  • Controlling blood pressure, managing anemia, and optimizing dialysis can help alleviate symptoms, including nausea, in ESRD patients 4, 1.
  • A palliative approach to ESRD is a reasonable alternative to dialysis, particularly for individuals with limited life expectancy, severe comorbid conditions, or those who wish to avoid medical interventions 4, 5.
  • Patients with ESRD should have advance directives, including documentation of situations in which they would no longer want dialysis 1.

References

4
Research

End-Stage Renal Disease: Medical Management.

American family physician, 2021

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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