Should sterile saline or sterile water be used to fill a urinary catheter balloon?

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Last updated: April 21, 2025View editorial policy

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From the Research

Sterile water should be used to fill catheter balloons, not sterile saline. When inflating a urinary catheter balloon, always use the manufacturer-recommended volume of sterile water (typically 5-10 mL for adult catheters). This is based on the study by 1, which found that the use of saline or glycine in catheter balloons has an equivalent deflation failure rate to using water, but the practical implication of the difference in deflation volume between water and saline is not apparent. However, other studies have suggested that sterile saline should be avoided because the salt crystals can precipitate over time and potentially obstruct the inflation channel, making it difficult or impossible to deflate the balloon when the catheter needs to be removed 2, 3.

The most recent and highest quality study, 1, found that there was no failure to deflate in all 600 catheters, and the median deflation volume for water, saline, and glycine was 9.0,9.2, and 9.1 mL, respectively. However, the study by 3 found that sterile water might be preferred if bulb inflation must be maintained for more than 5 days.

Some key points to consider when filling catheter balloons include:

  • Using the manufacturer-recommended volume of sterile water
  • Drawing up the sterile water using aseptic technique
  • Injecting the sterile water slowly into the inflation port
  • Following the specific volume recommendations for the particular catheter being used
  • Avoiding the use of sterile saline due to the potential for salt crystals to precipitate and obstruct the inflation channel.

Overall, the use of sterile water to fill catheter balloons is recommended due to its safety and effectiveness, as supported by the study by 1.

References

Research

Can normal saline be used to fill the balloon of a Foley catheter? The experience of a prospective randomized study in China.

International journal of urology : official journal of the Japanese Urological Association, 2004

Research

Optimal filling solution for silicone Foley catheter balloons.

The Canadian veterinary journal = La revue veterinaire canadienne, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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