What is the common brand name for amoxicillin‑clavulanate (co‑amoxiclav)?

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Common Brand Name for Amoxicillin-Clavulanate

The most widely recognized brand name for amoxicillin-clavulanate (co-amoxiclav) is Augmentin. 1, 2, 3

Brand Name Details

  • Augmentin is the established trade name for the combination of amoxicillin with clavulanic acid (also called clavulanate potassium), which has been available for over 20 years in clinical practice 2

  • The combination was introduced in the United States in 1984 specifically to enhance amoxicillin's activity by adding the β-lactamase inhibitor clavulanic acid 4

Available Formulations Under the Augmentin Brand

  • Augmentin ES-600: A high-dose pediatric formulation (90/6.4 mg/kg/day amoxicillin/clavulanate in two divided doses) approved in 2001 for persistent or recurrent acute otitis media in children 3, 4

  • Augmentin XR: An extended-release formulation (2000/125 mg twice daily) designed for adult respiratory tract infections caused by drug-resistant pathogens, available in the United States 2, 5

  • The original formulation combined amoxicillin and clavulanate in a 4:1 ratio, followed by a 7:1 ratio, with the high-dose pediatric formulation providing a 14:1 ratio 4

Clinical Context

  • The addition of clavulanic acid to amoxicillin preserves amoxicillin's activity against β-lactamase-producing bacteria, significantly expanding its antimicrobial spectrum 6

  • Augmentin maintains excellent activity against common respiratory pathogens including Streptococcus pneumoniae, Haemophilus influenzae (95-100% effectiveness), and Moraxella catarrhalis (100% effectiveness) 6

References

6
Guideline

Amoxicilina y Amoxicilina-Clavulánico

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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