How many milliliters of Motrin (ibuprofen) 100 mg/5 ml should be given per dose to a 60‑lb (≈27 kg) child?

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Ibuprofen Dosing for a 60-lb Child

For a 60-lb (approximately 27 kg) child, administer 13.5 mL of Motrin 100 mg/5 mL suspension per dose, which delivers 270 mg of ibuprofen based on the standard 10 mg/kg dosing recommendation. 1

Weight-Based Calculation

  • A 60-lb child weighs approximately 27.3 kg (60 ÷ 2.2 = 27.3 kg). 1
  • The American Academy of Pediatrics recommends 10 mg/kg per dose for pediatric ibuprofen dosing. 1, 2
  • For this child: 27.3 kg × 10 mg/kg = 273 mg per dose. 1
  • Using the 100 mg/5 mL concentration: (273 mg ÷ 100 mg) × 5 mL = 13.65 mL, which rounds to 13.5 mL for practical administration. 1

Dosing Schedule and Frequency

  • Administer ibuprofen every 6-8 hours as needed. 1, 3
  • The maximum frequency is 3-4 doses per 24 hours. 2, 3
  • Do not exceed 40 mg/kg/day (approximately 1,092 mg/day for this child). 2

Critical Safety Points

  • Record all dose times carefully to avoid accidentally exceeding the maximum recommended dose, especially if alternating with acetaminophen. 4
  • The maximum reduction in temperature occurs 3-4 hours after administration. 5
  • Ibuprofen is generally not recommended for infants under 6 months of age. 1
  • Ensure adequate hydration when administering ibuprofen. 6

Common Pitfalls to Avoid

  • Avoid "hidden sources" of NSAIDs in combination over-the-counter medications that could lead to inadvertent overdosing. 2
  • Do not combine ibuprofen with other NSAID medications without dose adjustment. 2
  • Oral administration is preferred over rectal routes due to more reliable and consistent absorption. 1

References

Guideline

Pediatric Acetaminophen and Ibuprofen Dosing Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Ibuprofen Dosing Guidelines for Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Ibuprofen Administration in Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

A general overview of the use of ibuprofen in paediatrics.

International journal of clinical practice. Supplement, 2003

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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