Is nausea a common side effect of Abilify (aripiprazole)?

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From the FDA Drug Label

The most common adverse reactions in adult patients in clinical trials (≥10%) were nausea, vomiting, constipation, headache, dizziness, akathisia, anxiety, insomnia, and restlessness The most common side effects of aripiprazole tablets in adults include: • Nausea • dizziness • vomiting • anxiety • constipation • insomnia • headache • restlessness • blurred vision • inner sense of restlessness/need to move (akathisia) • upper respiratory illness

Nausea is a common side effect of Abilify (aripiprazole), as evidenced by its inclusion in the list of most common adverse reactions in adult patients in clinical trials and the list of most common side effects in adults 1 1.

From the Research

Side Effects of Abilify (Aripiprazole)

  • Nausea is a commonly reported side effect of Abilify (aripiprazole) 2, 3, 4, 5
  • The frequency and severity of nausea may vary depending on the dose and individual patient response 2, 3
  • Other common side effects of Abilify include restlessness/akathisia, somnolence, headache, anxiety, insomnia, vomiting, and lightheadedness 2, 6, 3, 4, 5

Comparison with Other Treatments

  • Aripiprazole has been compared with other drug treatments, including lithium and haloperidol, in the treatment of acute manic or mixed episodes 5
  • The results of these comparisons suggest that aripiprazole is effective in reducing manic symptoms, but may cause more movement disorders and gastrointestinal disturbances than other treatments 5

Patient Response

  • Patient response to aripiprazole may vary, with some patients developing tolerance to the side effects over time 2
  • The drug has been shown to be effective in treating positive, negative, and cognitive symptoms of schizophrenia and schizoaffective disorder, with a relatively low risk of metabolic and endocrine alterations 3

References

Research

Aripiprazole.

Expert opinion on pharmacotherapy, 2005

Research

Aripiprazole.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003

Research

Aripiprazole alone or in combination for acute mania.

The Cochrane database of systematic reviews, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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