What is the likely cause and recommended management for a patient presenting with pimples inside the nostril?

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Nasal Vestibular Folliculitis (Nasal Furuncles)

The pimples inside your nose are most likely nasal furuncles (folliculitis), which are inflammatory nodules with overlying pustules caused by Staphylococcus aureus infection of hair follicles in the nasal vestibule. 1

Immediate Management

For small furuncles, apply moist heat to promote drainage—this is often sufficient as sole therapy. 1 Larger lesions require incision and drainage. 1

  • Systemic antibiotics are usually unnecessary unless extensive surrounding cellulitis or fever develops. 1
  • If antibiotics are needed due to surrounding cellulitis, the choice should account for local MRSA prevalence patterns 1

Understanding the Underlying Problem

The root cause is S. aureus colonization of your anterior nares (nasal vestibule). 1 Approximately 20-40% of the general population carries S. aureus in their nose, but only some carriers develop recurrent skin infections. 1, 2, 3

  • Nasal carriage serves as a reservoir for repeated infections 1, 2
  • The bacteria can colonize damaged skin barriers and cause follicular inflammation 2

Prevention of Recurrent Episodes

If you experience repeated nasal furuncles, the most effective strategy is eradicating nasal S. aureus carriage with topical mupirocin ointment applied twice daily to the anterior nares for the first 5 days of each month—this reduces recurrences by approximately 50%. 1

For more aggressive suppression:

  • Oral clindamycin 150 mg once daily for 3 months decreases subsequent infections by approximately 80% (for clindamycin-susceptible strains). 1
  • Mupirocin is significantly more effective than bacitracin for eradicating nasal S. aureus (94% vs 44% eradication rate). 4

Additional Preventive Measures for Outbreak Control

If multiple household members are affected or you have repeated episodes: 1

  • Bathe with chlorhexidine antibacterial soap
  • Thoroughly launder clothing, towels, and bedwear
  • Use separate towels and washcloths
  • Attempt eradication of staphylococcal carriage among all colonized household members

Critical Pitfalls to Avoid

Do not squeeze or manipulate nasal furuncles aggressively—the nasal vestibule has venous drainage to the cavernous sinus, and manipulation can theoretically lead to serious complications, though this is rare. 1

Avoid assuming this is acne—while S. aureus colonization rates are similar in acne patients and healthy controls (21.7% vs 26.6%), nasal vestibular lesions with pustules emerging through hair follicles are characteristic of folliculitis/furuncles, not acne. 5

When to Seek Urgent Care

Seek immediate medical attention if you develop: 1

  • Fever
  • Extensive surrounding redness or cellulitis spreading beyond the immediate area
  • Facial swelling
  • Vision changes or eye symptoms
  • Severe headache

These could indicate deeper infection requiring systemic antibiotics or more aggressive intervention.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Bacitracin versus mupirocin for Staphylococcus aureus nasal colonization.

Infection control and hospital epidemiology, 1999

Research

Staphylococcus aureus in Acne Pathogenesis: A Case-Control Study.

North American journal of medical sciences, 2012

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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