What is the CHADS2 score for a 64-year-old man with hypertension, diabetes mellitus, prior stroke/TIA, no congestive heart failure, and atrial fibrillation?

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CHADS₂ Score Calculation

This patient has a CHADS₂ score of 4 points.

Score Breakdown

The CHADS₂ scoring system assigns points as follows 1, 2:

  • C (Congestive Heart Failure): 0 points — No heart failure mentioned 1, 2
  • H (Hypertension): 1 point — Blood pressure 150/90 mmHg confirms hypertension 2
  • A (Age ≥75 years): 0 points — Patient is 64 years old, which does not meet the ≥75 threshold 1, 2
  • D (Diabetes Mellitus): 1 point — Known diabetic 1, 2
  • S₂ (Prior Stroke/TIA): 2 points — History of stroke carries doubled weight 1, 2

Total CHADS₂ Score: 0 + 1 + 0 + 1 + 2 = 4 points

Clinical Significance

A CHADS₂ score of 4 indicates very high stroke risk with an annual stroke rate of approximately 12.5% without anticoagulation 2. This score places the patient in the highest risk category, where the absolute benefit of anticoagulation substantially outweighs bleeding risk 1.

Critical Management Implications

Oral anticoagulation is strongly indicated for this patient 1, 2:

  • Either warfarin (target INR 2.0-3.0) or a direct oral anticoagulant (DOAC) should be initiated 2
  • DOACs are generally preferred over warfarin as first-line therapy given their superior safety profile 3
  • The prior stroke history alone (2 points) warrants anticoagulation regardless of other risk factors 1

Important Clinical Caveat

Do not confuse CHADS₂ with CHA₂DS₂-VASc: The CHADS₂ system awards 1 point only for age ≥75 years 2. Ages 65-74 do not receive a point in CHADS₂ (though they would in the newer CHA₂DS₂-VASc score) 4, 2. This is a common pitfall in clinical practice 2.

Blood pressure control is critically important in this patient receiving anticoagulation, as intracerebral hemorrhage risk is exquisitely sensitive to blood pressure management 1.

References

Guideline

Atrial Fibrillation Stroke Risk Assessment using CHADS₂ Score

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

CHADS₂ Scoring System and Clinical Implications

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

CHA₂DS₂-VASc Risk Stratification for Atrial Fibrillation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Related Questions

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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