From the Research
Introduction to Co-aleve (Naproxen) Dosing
Co-aleve, also known as Naproxen, is a non-steroidal anti-inflammatory drug (NSAID) used to treat various painful conditions, including acute postoperative pain and rheumatoid arthritis. The dosing of Naproxen can vary depending on the condition being treated and the formulation used (e.g., Naproxen or Naproxen sodium).
Dosing Information for Acute Postoperative Pain
For acute postoperative pain, the effective dose of Naproxen sodium is 550 mg, which is equivalent to 500 mg of Naproxen 1, 2. This dose has been shown to provide effective analgesia with a relatively low incidence of adverse events. Lower doses, such as 200 mg and 400 mg of Naproxen, may also provide effective pain relief, but the evidence is less clear 1, 2.
Dosing Information for Rheumatoid Arthritis
In the treatment of rheumatoid arthritis, Naproxen is often dosed at 750 mg daily 3. This dose has been compared to Meloxicam 7.5 mg daily in a clinical trial, with similar efficacy but a higher incidence of gastrointestinal side effects with Naproxen.
Over-the-Counter (OTC) Dosing and Safety
For OTC use, Naproxen sodium is available in various doses, ranging from 220 mg to 440 mg 4. A meta-analysis has confirmed the favorable safety profile of OTC Naproxen sodium, with an overall occurrence of adverse events comparable to or lower than placebo.
Treatment Considerations and Caveats
When prescribing or recommending Naproxen, it is essential to consider the individual patient's medical history, including any history of gastrointestinal disease, renal impairment, or other conditions that may affect the safety and efficacy of the medication. Patients should be advised to follow the recommended dosing instructions and to seek medical attention if they experience any adverse events.
Conclusion
In conclusion, the dose of Co-aleve (Naproxen) can vary depending on the condition being treated, but common doses include 500 mg for acute postoperative pain and 750 mg daily for rheumatoid arthritis. The safety profile of Naproxen is generally favorable, but patients should be monitored for potential adverse events, particularly gastrointestinal side effects.