For an elderly patient with ischemic heart disease who underwent coronary artery bypass grafting and then developed a surgical site infection progressing to septicemia and multiorgan failure resulting in death, which should be listed as the primary cause of death on the death certificate?

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Primary Cause of Death Documentation

Septicemia should be documented as the primary cause of death on this patient's death certificate. 1

Understanding Death Certificate Causation

The death certificate requires establishing a logical causal sequence from the underlying condition to the immediate cause of death—documenting what the patient died from, not merely what they died with. 2, 3 In this case, the causal chain progressed from surgical site infection → septicemia → multiorgan failure → death. 1

The primary cause of death represents the final disease or condition that directly resulted in death, not the underlying chronic condition that predisposed the patient to complications. 1 While ischemic heart disease was the underlying condition necessitating CABG, it was not the direct cause of death. 1

Why Septicemia is the Correct Answer

  • Septicemia directly caused the multiorgan failure that killed the patient, making it the primary cause despite the patient's cardiac history. 1
  • The American College of Cardiology/American Heart Association recommends that death should be attributed to the specific proximate cause rather than distant underlying conditions. 1
  • The progression from surgical site infection to septicemia to multiorgan failure represents a clear causal chain that supersedes the underlying cardiac disease in determining the primary cause of death. 1

Clinical Context Supporting This Determination

Post-operative sepsis carries exceptionally high mortality in cardiac surgery patients, particularly when progressing to multiorgan failure, with mortality rates of 32-46%. 1, 4 In the research literature, severe sepsis after cardiac surgery occurred in approximately 2% of patients, with 32% mortality—16-fold higher than those without sepsis. 4

In patients who develop sepsis-related multiorgan failure after cardiac surgery, the most frequent direct cause of death is unresolved sepsis or multisystem organ failure, rather than the pre-existing cardiac disease. 1

Why Other Options Are Incorrect

  • CABG (Option D) is a surgical procedure, not a disease process, and should never be listed as a cause of death. 3, 5
  • Ischemic heart disease (Option B) would be listed as a contributing condition in Part II of the death certificate, but not as the primary cause since it did not directly cause death. 1, 5
  • Congestive heart failure (Option C) was not mentioned in the clinical scenario and would represent a mechanism of death rather than the proximate cause in this septic patient. 1

Proper Death Certificate Documentation

The cause of death statement should read:

  • Immediate cause (Part I, Line A): Multiorgan failure
  • Due to (Part I, Line B): Septicemia
  • Due to (Part I, Line C): Surgical site infection
  • Other significant conditions (Part II): Ischemic heart disease, status post CABG 3, 5

References

Guideline

Primary Cause of Death: Septicemia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Death Certificate Completion for Elderly Patients in Hospice Care

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Cause of death. Proper completion of the death certificate.

Journal (American Medical Record Association), 1987

Research

Severe sepsis in cardiac surgical patients.

The European journal of surgery = Acta chirurgica, 1998

Research

Death certification: a primer. Part II--The cause of death statement.

South Dakota medicine : the journal of the South Dakota State Medical Association, 2014

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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