What is the optimal daily supplement schedule for reducing arterial plaque and promoting cardiovascular health?

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Last updated: February 15, 2025View editorial policy

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From the Research

Introduction to Cardiovascular Health

Cardiovascular health is a critical aspect of overall well-being, and reducing arterial plaque is a key factor in promoting cardiovascular health.

Optimal Daily Supplement Schedule

The optimal daily supplement schedule for reducing arterial plaque and promoting cardiovascular health involves a combination of vitamins and antioxidants.

  • Vitamin C has antioxidant and cardioprotective effects, as discussed in 1.
  • Vitamin D may confer cardiovascular protection, although the data is not entirely consistent, as noted in 1 and 2.
  • Coenzyme Q10 (CoQ10) supplementation has been shown to reduce oxidative stress and mortality from cardiovascular causes, as well as improve clinical outcomes in patients with cardiovascular disease, as reported in 3.
  • Vitamins K2 and D3 supplementation may have a protective role in the progression of coronary artery calcification, as suggested in 4.

Recommended Supplements and Dosages

The following supplements and dosages may be beneficial for reducing arterial plaque and promoting cardiovascular health:

  • CoQ10: supplementation for prolonged periods is safe and well-tolerated, with a significant increase in plasma concentration, as discussed in 3.
  • Vitamins K2 and D3: supplementation with 720 µg/day of vitamin K2 and 25 µg/day of vitamin D3 may slow down the calcification process, as proposed in 4.
  • Folic acid and certain B-vitamins (e.g., B1/B2/B6/B12) may reduce cardiovascular disease, heart failure, and/or stroke, as indicated in 1.

Caveats and Considerations

It is essential to note that:

  • High doses of fat-soluble vitamins (A/D/E/K) may be harmful, as warned in 1.
  • Niacin and beta-carotene may have deleterious effects, as reported in 1.
  • A balanced diet that emphasizes whole grains, fruits, vegetables, nuts, seeds, legumes/pulses, seafood, lean meats, and fish/seafood, while limiting ultra-processed foods, processed meats, and alcohol, is crucial for maintaining cardiovascular health, as recommended in 5.

Conclusion

In conclusion, a combination of vitamins and antioxidants, including vitamin C, vitamin D, CoQ10, and vitamins K2 and D3, may be beneficial for reducing arterial plaque and promoting cardiovascular health. However, it is crucial to consider the potential risks and limitations associated with high doses of certain vitamins and to maintain a balanced diet.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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