At which lumbar vertebral level should the erector spinae plane (ESP) block be performed for endoscopic spine surgery at the L5‑S1 level?

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Last updated: February 10, 2026View editorial policy

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ESP Block Level for Endoscopic Spine Surgery at L5-S1

For endoscopic spine surgery at L5-S1, perform the erector spinae plane (ESP) block at the L3 or L4 vertebral level bilaterally. This provides optimal coverage of the lumbosacral surgical site while minimizing the risk of motor blockade that can confound postoperative neurologic examination 1, 2.

Recommended Vertebral Level and Rationale

  • The L3 level is the preferred injection site for L5-S1 surgery, as demonstrated by fluoroscopic studies showing excellent anesthetic spread from L2 to L5 when injected at L3 3.

  • L4 level is an acceptable alternative, particularly when targeting the lower lumbar and sacral regions, as case series have shown effective analgesia for lumbosacral procedures with blocks performed at L4 4.

  • Avoid performing the block at L5 or below for L5-S1 surgery, as this increases the risk of ventral rami involvement and motor blockade without improving analgesic coverage 2.

Technical Considerations

Timing of Block Placement

  • Perform the block preoperatively in awake patients rather than intraoperatively under general anesthesia to allow immediate assessment of motor function and avoid confounding postoperative neurologic examination 2.

  • If performed intraoperatively, ensure the anesthetic is deposited superficial to the transverse process tip without breaching the intertransversarii muscle and ligament to favor dorsal spread and spare ventral rami motor fibers 2.

Guidance Modality

  • Ultrasound guidance is the standard approach for ESP blocks, allowing real-time visualization of needle placement and local anesthetic spread 1, 5.

  • Fluoroscopic guidance is an efficient alternative for spine surgeons, with average block placement time of 1.2 minutes and confirmed appropriate spread on intraoperative 3D imaging 3.

Bilateral vs. Unilateral

  • Bilateral ESP blocks are recommended for midline lumbosacral spine surgery to provide symmetric analgesia, as the dorsal rami innervate paraspinal structures bilaterally 1.

Local Anesthetic Dosing

  • Use 20-40 mL per side of long-acting local anesthetic (0.25-0.5% bupivacaine or ropivacaine) to ensure adequate cranio-caudal spread 1, 4.

  • A mixture of 20 mL bupivacaine 0.5%, 10 mL lidocaine 2%, and 10 mL normal saline (40 mL total per side) has been successfully used for hip and lumbar surgery 4.

  • Calculate safe maximum dose based on patient weight to prevent local anesthetic systemic toxicity 6.

Catheter vs. Single-Shot Technique

  • Single-injection ESP blocks are adequate for most endoscopic L5-S1 procedures, which are typically minimally invasive with shorter operative times 1.

  • Continuous catheter techniques should be reserved for more extensive open lumbosacral procedures requiring prolonged postoperative analgesia 1.

Expected Analgesic Coverage

The ESP block at L3-L4 provides analgesia through:

  • Blockade of dorsal rami of spinal nerves that innervate paraspinal muscles, posterior vertebral elements, and facet joints 1, 5.

  • Cranio-caudal spread typically extends 2-3 vertebral levels above and below the injection site, providing coverage from approximately T12 to L5 when injected at L3 3, 4.

  • Potential paravertebral and epidural spread has been demonstrated on MRI, though the clinical significance remains debated 4.

Critical Safety Considerations

Motor Function Preservation

  • The ESP block should NOT cause motor weakness when properly performed, as it primarily targets dorsal rami 1.

  • Transient motor blockade is a red flag indicating either incorrect needle placement with ventral rami involvement or inadvertent epidural/paravertebral spread requiring immediate neurologic assessment 2.

  • No interference with intraoperative neuromonitoring (somatosensory evoked potentials) has been reported with properly performed ESP blocks 1.

Common Pitfalls to Avoid

  • Do not inject too deep or medial, as breaching the intertransversarii muscle increases risk of ventral spread and motor blockade 2.

  • Avoid performing the block at the exact surgical level (L5 for L5-S1 surgery), as this provides no advantage and increases complication risk; instead, inject 1-2 levels cephalad 1, 2.

  • Do not rely solely on ESP block without multimodal analgesia, as combining with NSAIDs and acetaminophen provides superior pain control and opioid-sparing effects 1.

Integration with Multimodal Analgesia

  • Combine ESP block with scheduled NSAIDs and acetaminophen initiated preoperatively or intraoperatively and continued postoperatively 7, 1.

  • Reserve opioids for breakthrough pain only, as the ESP block significantly reduces postoperative opioid requirements and associated side effects 1.

  • Consider adjuvants such as dexamethasone to prolong block duration, though balance this against immunosuppression risks 6, 7.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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