Current COVID-19 Isolation Guidelines
If you test positive for COVID-19, isolate for at least 5 days from symptom onset (or from your positive test if asymptomatic), and you can end isolation when you've been fever-free for 24 hours without medications, your symptoms are improving, and ideally after a negative rapid antigen test. 1
Minimum Isolation Period
- Isolate for a minimum of 5 days from the day your symptoms started or from the day you tested positive if you have no symptoms 2, 1
- The 5-day period is based on current CDC guidelines that balance transmission risk with practical adherence 2
Criteria to End Isolation After 5 Days
You can end isolation after 5 days if ALL of the following are met:
- Fever-free for at least 24 hours without using fever-reducing medications (like acetaminophen or ibuprofen) 1
- Your symptoms are resolving or absent 1
- Ideally, you have a negative rapid antigen test 1
Extended Isolation (Up to 10 Days)
Continue isolating beyond 5 days if:
- Your symptoms persist or worsen 1
- You continue to have a fever 1
- Your rapid antigen test remains positive 1
- Research shows that 54% of people still test positive on antigen tests between days 5-9, with declining positivity over time 3
During Isolation: What You Must Do
Physical isolation requirements:
- Stay in a well-ventilated single room if possible, with the door closed 1, 4
- If a single room isn't available, maintain at least 1 meter (approximately 3 feet) distance from others 1, 4
- Restrict all activities to minimize contact with others 1, 4
Masking and hygiene:
- Wear an N95 mask (preferred) or surgical mask when around others, including household members 1, 4
- Clean your hands immediately after coughing, sneezing, or touching potentially contaminated surfaces 1, 4
- Avoid sharing personal items like toothbrushes, towels, dishes, and bed linens 1
Monitoring:
- Check your temperature and monitor symptoms daily 1, 4
- Seek immediate medical attention if: your temperature exceeds 100.4°F (38°C) persistently, breathing worsens, you develop shortness of breath, or signs of pneumonia appear 1, 4
After Ending Isolation (Days 6-10)
- Continue wearing a well-fitting mask around others through day 10 after symptom onset or positive test 3
- You may still be infectious during this period, even if symptoms have resolved 3
For Household Members and Caregivers
If you live with someone who has COVID-19:
- Caregivers should be healthy individuals without underlying medical conditions when possible 1, 4
- Wear an N95 mask (preferred) or surgical mask when in the same room as the infected person 1, 4
- Monitor your own temperature and symptoms closely 1, 4
- Clean and disinfect frequently touched surfaces daily using 500 mg/L chlorine-containing disinfectant 1
- Avoid direct contact with the patient's respiratory secretions 1
Testing Considerations
Rapid antigen testing:
- A negative rapid antigen test can help guide the decision to end isolation after day 5 1
- Antigen tests are most accurate within 5 days of symptom onset 1
- A positive antigen test has high specificity and doesn't need confirmation 1
- Research shows antigen test positivity correlates with infectiousness 3
Important caveat: You are more likely to test positive on days 5-9 if you have symptomatic infection, haven't been vaccinated, or haven't had prior COVID-19 infection 3
Common Pitfalls to Avoid
- Don't count day 0 incorrectly: Day 0 is the day symptoms started or the day of your positive test (if asymptomatic), not the day before 2
- Don't use fever-reducing medications to artificially meet the fever-free requirement – you must be fever-free without these medications 1
- Don't assume you're not infectious after 5 days just because you feel better – continue masking through day 10 3
- Don't use public transportation when seeking medical care – use a private vehicle with windows open or an ambulance 1
Special Considerations for Athletes and Return to Exercise
If you're an athlete or regularly engage in intense exercise:
- For asymptomatic COVID-19: Resume training after 3 days of exercise abstinence during self-isolation 2
- For mild non-cardiopulmonary symptoms (fever, chills, fatigue, muscle aches): Resume training after symptom resolution 2
- For cardiopulmonary symptoms (chest pain, shortness of breath, palpitations, lightheadedness): Get cardiac evaluation before resuming intense exercise 2
- Use a graded return-to-exercise program rather than immediately resuming full intensity 2