There are no official guidelines to assist in answering this question. I will search for relevant research papers instead.
From the FDA Drug Label
CONTRAINDICATIONS Vancomycin hydrochloride for injection is contraindicated in patients with known hypersensitivity to this antibiotic. The contraindications for Vancomycin are:
- Hypersensitivity to the antibiotic 1
From the Research
Contraindications for Vancomycin
The following are contraindications for vancomycin:
- Hypersensitivity to vancomycin 2, 3, 4
- Nephrotoxicity, especially with high doses or prolonged therapy 2, 3, 5
- Ototoxicity, especially with high doses or prolonged therapy 2, 3
- Phlebitis 2
- Red man syndrome, a hypersensitivity reaction 2, 3
- Neutropenia, a bone marrow effect 2, 3
- Interstitial nephritis 2
Special Considerations
Vancomycin is not recommended for use in patients with certain conditions, such as:
- Renal impairment, as it may increase the risk of nephrotoxicity 3, 5
- Hearing loss, as it may increase the risk of ototoxicity 3
- Pregnancy or breastfeeding, as there is limited data on its safety in these populations
Dosage and Administration
Vancomycin should be used with caution and under close monitoring, especially in patients with renal impairment or those receiving high doses or prolonged therapy 2, 3, 5. The dosage and administration of vancomycin should be individualized based on the patient's condition and response to treatment.