From the Research
Treatment of persistent orgasms, also known as persistent genital arousal disorder (PGAD), should prioritize a multidisciplinary approach, including medications such as pregabalin or duloxetin, as well as pelvic floor physical therapy and psychological support, as suggested by the most recent and highest quality study 1.
Key Considerations
- The condition is rare and debilitating, with a scarcity of systematic research and limited evidence-based data, emphasizing the need for careful diagnostics and counseling 2, 1.
- A multidisciplinary treatment approach is recommended, addressing both physical and psychiatric concerns, and considering the patient's distressing and psychiatric symptoms 3, 1.
- Medications such as selective serotonin reuptake inhibitors (SSRIs) may be used with caution, as they can induce or worsen PGAD in some cases 2.
- Pelvic floor physical therapy and psychological support through cognitive behavioral therapy can help manage symptoms and emotional distress associated with the condition 3, 1.
Treatment Options
- Pregabalin or duloxetin may be considered as potential treatment options, as they can inhibit sexual excitation and/or modulate sensory perception 2.
- Other medications, such as antidepressants or anticonvulsants, may also be effective in reducing unwanted arousal, but should be used with caution and under close supervision 2, 1.
- Non-pharmacological interventions, such as applying ice packs to the genital area, practicing distraction techniques, or engaging in moderate physical activity, can provide immediate relief during episodes 3, 1.
Importance of Multidisciplinary Approach
- The underlying causes of persistent orgasms vary widely, from neurological conditions to medication side effects to pelvic floor dysfunction, requiring a comprehensive and individualized treatment plan 3, 1.
- Consultation with specialists in sexual medicine, neurology, or urogynecology may be necessary to address potential underlying causes and optimize treatment response 3, 1.