What is the diagnosis for a 2-year-old with recurrent unilateral localized erythema (redness) of the cheek that is fluctuating?

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Differential Diagnosis for a 2-year-old with Recurrent Localized Red Cheek Unilateral Fluctuating

  • Single most likely diagnosis
    • Parotid gland infection or parotitis: This condition is common in children and can cause recurrent, localized redness and swelling of the cheek, often unilateral. The fluctuating nature suggests an abscess or a collection of pus.
  • Other Likely diagnoses
    • Erythema infectiosum (Fifth disease): Although it typically presents with a "slapped-cheek" appearance, it can cause unilateral redness and is common in children.
    • Contact dermatitis: This could cause localized redness and irritation, especially if the child has come into contact with an allergen or irritant on one side of the face.
    • Impetigo: A highly contagious bacterial skin infection that can cause red, crusty sores and can appear on the face, potentially causing unilateral symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Cellulitis: A bacterial skin infection that can spread rapidly and cause serious complications if not treated promptly. It can present with redness, swelling, and warmth of the skin.
    • Osteomyelitis of the facial bones: Although rare, this infection of the bone can cause localized redness, swelling, and pain, and requires prompt treatment to prevent serious complications.
    • Orbital cellulitis: An infection of the tissues surrounding the eye, which can cause redness, swelling, and protrusion of the eye, and can lead to serious complications if not treated promptly.
  • Rare diagnoses
    • Sarcoidosis: A condition that can cause skin lesions, including on the face, but is rare in young children.
    • Lupus erythematosus: An autoimmune disease that can cause a butterfly-shaped rash on the face, but is uncommon in children as young as 2 years old.
    • Angioedema: A condition that causes swelling of the skin and mucous membranes, which can be unilateral and affect the face, but is less common in this age group without a clear trigger.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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