What is the out‑of‑pocket cost of Ozempic (semaglutide) when using the savings card?

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Last updated: February 11, 2026View editorial policy

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Cost of Ozempic with Savings Card

For commercially insured patients, the Ozempic manufacturer savings card reduces out-of-pocket costs to as low as $25 per month, though Medicare and Medicaid patients are not eligible for this program. 1

Eligibility and Restrictions

  • Commercial insurance patients can access manufacturer copay savings cards that significantly reduce out-of-pocket expenses, with programs available directly through the manufacturer's website 1
  • Medicare patients are explicitly excluded from manufacturer copayment savings programs, which can result in substantially higher costs depending on their plan's formulary tier 1
  • Medicaid patients typically have minimal copayments ($0-$5) once prior authorization is approved, making savings cards unnecessary for this population 1

Cost Without Savings Programs

  • The average wholesale price (AWP) for Ozempic is approximately $1,619 per 30-day supply, representing the list price before any discounts or insurance coverage 1
  • The National Average Drug Acquisition Cost (NADAC) is approximately $1,296 per 30-day supply, reflecting actual acquisition costs at the pharmacy level 1

Medicare-Specific Challenges

  • Medicare patients face the highest out-of-pocket burden, with copayments potentially ranging from 5% to 25% of the drug cost depending on their plan's tier structure 1
  • In some cases, Medicare patients have encountered copayments as high as $1,800 when semaglutide products are classified under specialty tier 5 formularies 1
  • Medicare patients in the initial deductible phase may pay 100% of the drug cost until their deductible is met 1

Alternative Cost-Reduction Strategies

  • Discount programs like GoodRx, CostPlus, and SingleCare may provide lower-cost alternatives for some patients, though availability varies by medication and location 1
  • Financial navigation services and social workers can help patients identify assistance programs and strategize medication affordability 1
  • For Medicare beneficiaries meeting specific income thresholds (income under $17,226 and assets under $9,470), the full subsidy program caps brand-name copays at $8.95, potentially reducing annual costs to under $50 1

Common Pitfalls to Avoid

  • Do not assume all patients can access manufacturer savings cards—always verify insurance type before discussing expected costs, as Medicare and Medicaid patients face different cost structures 1
  • Prior authorization requirements can delay treatment initiation and may result in claim rejections even with savings cards, requiring clinical documentation and appeals 1
  • State laws may restrict the use of manufacturer copay assistance programs in certain jurisdictions 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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