A 42-year-old woman with pelvic pressure, bloating, lower abdominal heaviness, prolonged heavy menstrual bleeding, and ultrasound showing a uterine fibroid: which type is most likely? A. Cervical fibroid B. Parasitic fibroid C. Subserosal fibroid D. Submucosal fibroid

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Submucosal Fibroid (Answer D)

The most likely diagnosis is a submucosal fibroid, given the combination of prolonged heavy menstrual bleeding (menorrhagia) with pelvic pressure and bloating in this 42-year-old woman. 1

Clinical Reasoning Based on Symptom-Location Correlation

The key to this diagnosis lies in understanding which fibroid location causes which symptoms:

Heavy Menstrual Bleeding Points Specifically to Submucosal Location

  • Submucosal fibroids are specifically and strongly associated with menorrhagia because they project into the uterine cavity and directly affect the endometrial surface. 1

  • These fibroids cause abnormal uterine bleeding through multiple mechanisms including enlargement of the uterine cavity, impairment of blood supply to the endometrium, and endometrial atrophy and ulceration. 1

  • Menorrhagia is the most frequent symptom of uterine fibroids overall, often resulting in iron deficiency anemia. 2

  • Transvaginal ultrasound has excellent diagnostic accuracy for submucosal fibroids specifically, with 90% sensitivity and 98% specificity. 1, 3, 4

Why the Other Options Are Less Likely

Subserosal fibroids (Option C):

  • Subserosal fibroids typically do not cause menorrhagia, but are more associated with bulk symptoms such as pelvic pressure alone. 1, 3
  • While this patient has pelvic pressure, the dominant feature of prolonged heavy menstrual bleeding makes subserosal location unlikely. 1

Cervical fibroids (Option A):

  • Cervical fibroids are rare, accounting for less than 5% of all uterine fibroids. 3
  • They more commonly present with dyspareunia, urinary obstruction, or vaginal discharge rather than heavy menstrual bleeding. 3
  • They have high treatment failure rates with interventions like uterine artery embolization and are not characteristically associated with menorrhagia as a primary presenting symptom. 1

Parasitic fibroids (Option B):

  • Parasitic fibroids are extremely rare and represent fibroids that have detached from the uterus and obtained blood supply from other structures. 5
  • They are commonly diagnosed as incidental findings during radiologic or surgical procedures, not as a cause of menorrhagia. 5
  • This diagnosis would not explain the heavy menstrual bleeding pattern. 5

Diagnostic Confirmation

  • The ultrasound should be reviewed to confirm whether the fibroid distorts the endometrial cavity—this is the hallmark of submucosal location. 3

  • Intramural fibroids that abut the endometrium can cause menorrhagia, but the bleeding is typically less severe than that produced by true submucosal lesions. 3

Treatment Implications

  • Hysteroscopic myomectomy is specifically indicated for submucosal fibroids in patients desiring uterus preservation. 1

  • Patients with significant intramural or subserosal fibroid burden causing bulk symptoms are less likely to experience symptom relief from hysteroscopic myomectomy. 1

References

Guideline

Fibroid Location and Symptoms

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Clasificación y Diagnóstico de Miomas Uterinos

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Distinguishing Uterine Fibroid from Uterine AVM

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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