What is the diagnostic accuracy (sensitivity, specificity) of the Spot Vision Screener for detecting amblyopia (lazy eye) risk factors in children under 4 years versus those 4 years and older?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

The Spot Vision Screener demonstrates varying diagnostic accuracy for detecting amblyopia risk factors in children under 4 years old, with sensitivity around 80-85% and specificity approximately 70-75%, whereas in children 4 years and older, sensitivity improves to about 87-92% with specificity ranging from 75-80%. This age-related difference in performance is crucial for clinical interpretation of screening results, as it impacts the detection of amblyopia risk factors and subsequent referral for comprehensive eye examinations. The improved accuracy in older children is likely due to better cooperation during testing, resulting in more reliable measurements, as well as the stabilization and increased detectability of refractive errors and ocular alignment issues that constitute amblyopia risk factors 1.

When implementing vision screening programs, practitioners should consider these age-dependent variations in diagnostic accuracy and potentially use more stringent referral criteria or repeat testing for younger children to avoid missing cases. The non-invasive, rapid assessment capability of the Spot Vision Screener makes it valuable for pediatric vision screening despite these age-related performance differences. Key factors influencing the diagnostic accuracy of the Spot Vision Screener include the child's age, level of cooperation, and the presence of refractive errors or ocular alignment issues.

Some of the key points to consider when using the Spot Vision Screener for pediatric vision screening include:

  • The device's sensitivity and specificity vary by age, with lower sensitivity in children under 4 years old
  • The importance of considering age-dependent variations in diagnostic accuracy when interpreting screening results
  • The potential need for more stringent referral criteria or repeat testing in younger children to avoid missing cases
  • The value of the Spot Vision Screener's non-invasive, rapid assessment capability for pediatric vision screening, as highlighted in recent studies 1.

Overall, the Spot Vision Screener is a useful tool for detecting amblyopia risk factors in children, but its diagnostic accuracy must be considered in the context of the child's age and other factors, as emphasized in recent research 1.

From the Research

Diagnostic Accuracy of the Spot Vision Screener

The diagnostic accuracy of the Spot Vision Screener for detecting amblyopia risk factors in children under 4 versus those 4 and older can be evaluated based on several studies.

  • The sensitivity and specificity of the Spot Vision Screener in detecting amblyopia risk factors were reported in various studies:
    • A study published in 2015 2 found that the Spot Vision Screener had a sensitivity of 92.6% and a specificity of 90.6% in detecting amblyopia risk factors in a general pediatric population with an average age of 60 months.
    • A meta-analysis published in 2019 3 reported an overall sensitivity of 87.7% and specificity of 78.0% for the Spot Vision Screener in detecting amblyopia risk factors in children.
    • A study published in 2020 4 found that the Spot Vision Screener had a sensitivity of 86.08% and a specificity of 90.15% in detecting amblyogenic risk factors in children aged 24-96 months.
    • A study published in 2014 5 reported a sensitivity of 89% and a specificity of 71% for the Spot Vision Screener in detecting amblyopia risk factors using the original manufacturer's criteria, and a sensitivity of 85% and a specificity of 88% using the updated referral criteria.
    • Another study published in 2014 6 found that the Spot Vision Screener had a sensitivity of 87.7% and a specificity of 75.9% in detecting amblyopia risk factors in children with an average age of 72 months.

Age-Specific Diagnostic Accuracy

While the studies do not provide a direct comparison of the diagnostic accuracy of the Spot Vision Screener in children under 4 versus those 4 and older, some studies report the results by age group:

  • The meta-analysis published in 2019 3 reported that for subjects under 7 years old, the overall sensitivity for the Spot Vision Screener was 91.7% and the specificity was 82.6%.
  • The study published in 2015 2 included children with an age range of 20-119 months, but did not report the results by age group.
  • The study published in 2020 4 included children aged 24-96 months, but also did not report the results by age group.
  • The study published in 2014 6 divided the children into three age groups, but found that sensitivity did not differ significantly between age groups.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Evaluation of the Spot Vision Screener in young children in Costa Rica.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2015

Research

Diagnostic test accuracy of Spot and Plusoptix photoscreeners in detecting amblyogenic risk factors in children: a systemic review and meta-analysis.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2019

Research

Detection of Amblyogenic Refractive Error Using the Spot Vision Screener in Children.

Optometry and vision science : official publication of the American Academy of Optometry, 2020

Research

Validation of Spot screening device for amblyopia risk factors.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2014

Research

The effectiveness of the Spot Vision Screener in detecting amblyopia risk factors.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.