For a healthy adult with diarrhea who also ate a normal dinner, is the 480 mg of sodium in one serving of Gatorade Lyte sufficient to replace the sodium lost and adequately rehydrate?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 11, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Gatorade Lyte is NOT adequate for rehydration after diarrhea

No, 480 mg of sodium (approximately 21 mEq/L) in Gatorade Lyte is insufficient for proper rehydration after diarrhea, and the Infectious Diseases Society of America explicitly warns against using Gatorade or similar sports drinks for this purpose. 1

Why Sports Drinks Fail for Diarrhea Rehydration

  • The sodium concentration in Gatorade Lyte is far too low - at approximately 21 mEq/L, it contains less than half the minimum 50 mEq/L sodium required in proper oral rehydration solutions (ORS). 1, 2

  • Properly formulated ORS must contain 50-90 mEq/L of sodium to effectively replace losses and leverage the coupled sodium-glucose transport mechanism that enables water absorption during diarrhea. 1, 2

  • Popular beverages like Gatorade lack the appropriate electrolyte composition and should not be used for rehydration, as they may actually worsen the situation due to inadequate sodium and excessive sugar content. 1, 2

What You Actually Need

For Mild to Moderate Dehydration (Most Common)

  • Use a proper ORS containing 50-90 mEq/L sodium - commercially available options include Pedialyte, CeraLyte, or WHO oral rehydration salts. 1

  • Adults should consume 2-4 liters of ORS to achieve initial rehydration, then replace ongoing losses with additional ORS as needed (up to 2 L/day). 1

  • Replace each loose stool with approximately 240 mL of ORS to maintain hydration as diarrhea continues. 1

Sodium Content in Diarrheal Losses

  • Diarrheal fluid typically contains 50-130 mEq/L of sodium depending on the cause - secretory diarrheas (like cholera or infectious causes) average 128 mEq/L, while other causes range from 53-88 mEq/L. 3

  • Your dinner's sodium content is irrelevant - dietary sodium from food does not replace the specific electrolyte losses in diarrheal fluid, which requires the coupled sodium-glucose transport mechanism that only properly formulated ORS provides. 1

When to Seek Medical Care

  • If no improvement occurs within 48 hours of starting proper ORS rehydration. 1

  • If warning signs develop: high fever (>38.5°C), frank blood in stools, severe vomiting preventing fluid intake, or signs of severe dehydration (altered mental status, rapid pulse, poor perfusion). 1, 2

The Bottom Line

Switch from Gatorade Lyte to a proper ORS immediately - the 480 mg sodium in one serving represents inadequate replacement therapy that could prolong your illness or lead to worsening dehydration. 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Hydration Therapy Dose in Severe Dehydration

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.