From the Research
To prepare a 0.8 g dose of sevelamer from a 2.4 g packet, you should divide the packet into three equal portions, and use one portion for your dose. This can be done by carefully emptying the packet onto a clean, dry surface and using a card or spatula to divide the powder into three equal piles. Each pile will contain approximately 0.8 g of sevelamer (2.4 g ÷ 3 = 0.8 g). Take one portion for your dose and store the remaining two portions in separate, sealed containers for later use. Make sure to label these containers with the medication name, dose (0.8 g), and date of preparation. When ready to take the medication, mix your 0.8 g portion with water or another appropriate liquid as directed by your healthcare provider, and consume immediately. This division method works because sevelamer powder is generally uniform in consistency, allowing for reasonably accurate dosing when divided equally 1. However, if precise dosing is critical, consult your pharmacist about alternative methods or whether they can prepare individual doses for you. It's also important to note that sevelamer has been shown to be effective in reducing serum phosphorus levels and improving outcomes in patients with chronic kidney disease, including those on hemodialysis 2. The most recent and highest quality study available supports the use of sevelamer as an add-on or alternative therapy to calcium-based phosphate binders, which is associated with improved survival in patients on maintenance hemodialysis 2. Key points to consider when preparing and taking sevelamer include:
- Divide the 2.4 g packet into three equal portions to achieve the 0.8 g dose
- Use a clean, dry surface and a card or spatula to divide the powder
- Label and store the remaining portions for later use
- Mix the 0.8 g portion with water or another appropriate liquid as directed by your healthcare provider
- Consult your pharmacist if precise dosing is critical or for alternative preparation methods.