What are the dose and duration of olanzapine and baclofen for intractable hiccup management?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 16, 2025 • View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Dose and Duration of Olanzapine for Intractable Hiccup Management

  • The dose of olanzapine is not specifically mentioned in the context of intractable hiccup management in the provided studies 1, 2, 3, 4, 5.
  • However, the starting dose of olanzapine is mentioned as 10 mg in a study focusing on its general use 3.
  • Another study mentions that the dose of olanzapine can be adjusted in 5-mg increments or decrements within the allowed dose range of 5-20 mg/day 4.
  • A dose-response meta-analysis of antipsychotic drugs, including olanzapine, suggests that the 95% effective dose of olanzapine is 15.2 mg/day, with a dose equivalent to 1 mg of oral risperidone being 2.4 mg 5.

Dose and Duration of Baclofen for Intractable Hiccup Management

  • The dose of baclofen for intractable hiccup management is mentioned as 5-10 mg, three times daily, in a case report of a heart transplant recipient 1.
  • The duration of baclofen treatment in this case was 6 weeks, after which it was titrated down and discontinued due to severe central nervous system side effects and lack of efficacy in stopping the hiccups 1.

References

1
Research

Low-dose gabapentin for intractable hiccups in a heart transplant recipient.

Progress in transplantation (Aliso Viejo, Calif.), 2011

3
Research

Focus on olanzapine.

Current medical research and opinion, 1999

4
Research

A 4-week, double-blind comparison of olanzapine with haloperidol in the treatment of amphetamine psychosis.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005

Related Questions

What are the recommended dose and duration of olanzapine and baclofen for treating intractable hiccups?
What is the dose and duration of olanzapine used for the management of intractable hiccups?
In a 9‑year‑old child presenting with acute aggression, is a single 5 mg oral disintegrating olanzapine dose appropriate, or should a lower dose be used?
What is the antipsychotic of choice for methamphetamine-induced psychosis?
What alternative medication can be used for a patient with expected side effects from olanzapine (Olanzapine) and lurasidone (Lurasidone), excluding clozapine (Clozapine)?
What is the appropriate needle size for a Transjugular Intrahepatic Portosystemic Shunt (TIPS) procedure?
What is the dose and duration of olanzapine used for the management of intractable hiccups?
What are the dose and duration of olanzapine and baclofen for intractable hiccups management?
Can Tranexamic Acid (TXA) stop a gastrointestinal (GI) bleed?
What causes gasping with open mouth breathing and normal vital signs?
Is agonal breathing with normal vital signs an indicator of impending death?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.

Ask Question