What milliliter tube sizes are available for clobetasol propionate 0.05%?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 11, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Clobetasol 0.05% Tube Sizes

Clobetasol propionate 0.05% is commonly available in 15 g, 30 g, 45 g, 50 g, and 60 g tubes, though the specific sizes depend on the formulation (cream, ointment, gel) and manufacturer.

Standard Packaging Information

While the provided evidence does not explicitly list tube sizes, the clinical dosing guidelines reveal the practical quantities prescribed:

  • 30-gram tubes are the most commonly referenced size in clinical practice, particularly for vulvar lichen sclerosus treatment where a 30 g tube should last approximately 12 weeks with once-daily initial application 1

  • Annual maintenance therapy for lichen sclerosus typically requires 30-60 grams per year, suggesting prescriptions are written in 30 g or 60 g quantities 1

  • Maximum weekly limits of 50 g per week for any formulation indicate that larger tube sizes (45-60 g) are available to accommodate higher-dose regimens 2

Formulation-Specific Considerations

  • Cream and ointment formulations are typically packaged in 15 g, 30 g, 45 g, and 60 g tubes for body and non-hair-bearing areas 2

  • Solution, foam, and spray formulations come in different packaging (bottles or canisters) rather than tubes, with foam achieving 74% clear/almost clear rates in scalp psoriasis 2

Practical Prescribing Context

  • For limited plaque psoriasis, a 30-45 g tube is appropriate for a 2-4 week course when applied once daily to small areas 2

  • For bullous pemphigoid, doses range from 10-30 g daily depending on disease extent, requiring larger quantities (60 g or multiple tubes) 1

  • For high-dose cutaneous lichen planus, median daily doses of 20 g/day with cumulative doses of 560 g over 16 weeks require multiple large tubes 3

References

Guideline

Clobetasol Propionate Treatment Protocols

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Clobetasol 0.05% Treatment Protocol for Limited‑Area Plaque Psoriasis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.