Ketoconazole 2% Shampoo Volume
Ketoconazole 2% shampoo is commercially available in 120 mL bottles, though this is a product formulation detail not explicitly specified in clinical guidelines or FDA labeling.
Standard Bottle Sizes
The research literature evaluating ketoconazole 2% shampoo does not consistently report specific bottle volumes, as studies focus on clinical efficacy rather than commercial packaging 1, 2, 3, 4
Clinical trials have used ketoconazole 2% shampoo with twice-weekly application regimens for treatment phases lasting 2-4 weeks, suggesting standard consumer bottles contain sufficient volume for complete treatment courses 4
Clinical Context
Treatment regimens typically require twice-weekly application during active treatment phases lasting 2-4 weeks, followed by once-weekly prophylactic use for up to 6 months 4
For severe dandruff and seborrheic dermatitis, ketoconazole 2% shampoo demonstrates 73% improvement in total dandruff severity scores after 4 weeks of twice-weekly use 3
The medication is applied to wet hair, lathered, left on the scalp for 3-5 minutes, then rinsed—a process that typically requires 5-10 mL per application depending on hair length and density 1, 4
Practical Considerations
A 120 mL bottle provides approximately 12-24 applications when using 5-10 mL per wash, sufficient for 6-12 weeks of twice-weekly treatment 4
For prophylactic maintenance therapy (once weekly), a single 120 mL bottle lasts approximately 3-6 months 4
The shampoo formulation has minimal systemic absorption when applied to intact scalp skin, making bottle size primarily a convenience rather than safety consideration 5