What volume tube is erythromycin ophthalmic ointment dispensed in?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 11, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Erythromycin Ophthalmic Ointment Dispensing Volume

Erythromycin ophthalmic ointment 0.5% is commercially dispensed in 3.5 gram (1/8 oz) tubes for multi-dose use, or in 1 gram single-use containers. 1

Available Package Sizes

The FDA-approved product is supplied in two configurations:

  • 3.5 gram (1/8 oz) tamper-resistant tube – This is the standard multi-dose tube size (NDC 24208-910-55) 1
  • 1 gram tin container – Available in cartons of 50 units (NDC 24208-910-19) 1

Clinical Context for Neonatal Prophylaxis

For neonatal ocular prophylaxis, single-use tubes or ampules are strongly preferred over multi-use containers to minimize contamination risk. 2

  • The 1 gram single-use format is specifically designed for hospital use where multiple newborns require prophylaxis 1
  • The 3.5 gram tube, while commercially available for outpatient prescriptions, presents contamination concerns when used for multiple neonates 3
  • Some institutions have historically repackaged the 3.5 gram tubes into tuberculin syringes to create unit-dose preparations, though this practice requires appropriate compounding facilities 3

Storage Requirements

Both formulations must be stored between 15-25°C (59-77°F) and kept out of reach of children 1

References

Guideline

CDC Recommendations for Neonatal Ocular Prophylaxis with Erythromycin

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Unit dose erythromycin ophthalmic ointment for neonatal ocular prophylaxis.

JOGN nursing; journal of obstetric, gynecologic, and neonatal nursing, 1984

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.