What is the cause of a widened QRS complex in a patient with a right bundle branch block (RBBB)?

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Last updated: April 22, 2025View editorial policy

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From the Guidelines

Right bundle branch block (RBBB) is characterized by a widened QRS complex on an ECG due to delayed electrical activation of the right ventricle, resulting in a QRS duration greater than 120 milliseconds, as defined in the 2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay 1.

Key Features of RBBB

  • Delayed electrical activation of the right ventricle
  • Widened QRS complex on ECG
  • QRS duration greater than 120 milliseconds
  • Characteristic ECG pattern shows an RSR' pattern in the right precordial leads (V1-V3) and wide S waves in the lateral leads (I, aVL, V5-V6)

Clinical Implications

  • RBBB may occur in healthy individuals or indicate underlying cardiac disease such as coronary artery disease, cardiomyopathy, or congenital heart defects
  • No specific treatment is needed for isolated RBBB, but evaluation for underlying heart disease may be warranted depending on clinical context, as recommended in the 2018 ACC/AHA/HRS guideline 1

Diagnosis and Evaluation

  • ECG is the primary diagnostic tool for RBBB
  • Evaluation for underlying heart disease may include additional tests such as echocardiography, stress testing, or cardiac catheterization, as indicated in the 2018 ACC/AHA/HRS guideline 1

Management

  • No specific treatment is needed for isolated RBBB
  • Evaluation and management of underlying heart disease may be necessary, as recommended in the 2018 ACC/AHA/HRS guideline 1 and the 2019 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: executive summary 1

From the Research

Right Bundle Branch Block and QRS Complex

  • The QRS complex is prolonged in right bundle branch block (RBBB), with a duration of more than 0.12 seconds 2.
  • The QRS complex in RBBB typically shows an RR' or rR' pattern in lead V1, with widened S waves in leads exploring the left ventricle (SI, aVL, V5, and V6) 2.
  • A delay in the appearance of the intrinsic deflection of more than 0.08 seconds may be observed in the right precordial leads, and negative T waves with ST depression may be seen in V1 and sometimes in V2 2.

Effect of Right Bundle Branch Block on QRS Amplitudes

  • RBBB is associated with an increase in initial QRS forces (RV1, RV2, and QV6) but significant decreases in mean mid-QRS amplitudes that reflect left ventricular depolarization (RaVL, SV1, SV3, RV5, and RV6) 3.
  • All late QRS forces are increased with RBBB (R'V1, SV5, SI) 3.
  • Combined voltages used for left ventricular hypertrophy (LVH) criteria are significantly reduced by RBBB, including Sokolow-Lyon voltage and Cornell voltage 3.

Clinical Significance of Right Bundle Branch Block

  • RBBB may have hemodynamic consequences in cardiac failure with associated asynchrony of the left ventricle or in certain cases of right ventricular dilatation encountered in congenital heart disease 2.
  • The prognosis of RBBB in the absence of underlying cardiac disease is generally good, but it may be poor in other cases, particularly coronary artery disease 2, 4, 5.
  • RBBB is associated with increased cardiovascular morbidity and mortality, and its presence in patients with suspected acute coronary syndromes may indicate a need for further evaluation and potential acute invasive evaluation 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[Right bundle branch block: electrocardiographic and prognostic features].

Archives des maladies du coeur et des vaisseaux, 2005

Research

Effect of right bundle branch block on electrocardiographic amplitudes, including combined voltage criteria used for the detection of left ventricular hypertrophy.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2006

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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