What causes nocturnal headaches localized behind the eyes, exacerbated by temperature fluctuations?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Headaches Behind Eyes at Night, Worsened by Temperature Changes

  • Single Most Likely Diagnosis
    • Migraines: Often characterized by headaches that can occur at any time, including night, and can be exacerbated by various factors including temperature changes. The pain is typically unilateral but can be bilateral and is often described as being behind the eyes.
  • Other Likely Diagnoses
    • Tension Headaches: While typically less severe than migraines, tension headaches can occur at night and may worsen with stress or environmental changes, including temperature.
    • Sinusitis: Inflammation of the sinuses can cause pain behind the eyes, especially if the ethmoid sinuses are involved. Temperature changes can exacerbate sinus pressure.
    • Cluster Headaches: These are severe headaches that occur in clusters or cycles, often waking the patient from sleep. They are typically one-sided and can be felt behind the eye.
  • Do Not Miss Diagnoses
    • Temporal Arteritis (Giant Cell Arteritis): Although less common, this condition is critical to diagnose due to the risk of blindness. It typically presents with headache, jaw claudication, and visual disturbances, and can be exacerbated by temperature changes.
    • Acute Angle-Closure Glaucoma: A medical emergency that can cause severe eye pain, often described as being behind the eye, and can be associated with nausea, vomiting, and blurred vision. Temperature changes or other factors that affect intraocular pressure can precipitate an attack.
  • Rare Diagnoses
    • Trigeminal Neuralgia: Characterized by sudden, severe, shock-like pain around the eyes, lips, or nose mainly because of abnormal blood vessels pressing on the trigeminal nerve in the head. It's less likely to be directly related to temperature changes but can be considered in the differential for severe, episodic facial pain.
    • Idiopathic Intracranial Hypertension (IIH): Can cause headaches that worsen with recumbency and may have visual disturbances. While not directly linked to temperature changes, it's a rare condition that could potentially cause the described symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.