Differential Diagnosis for Rash from Tretinoin (Assuming "Tresebia" Refers to a Topical Retinoid Like Tretinoin)
- Single Most Likely Diagnosis:
- Irritant Contact Dermatitis: This is the most likely diagnosis due to the common side effect of topical retinoids like tretinoin causing skin irritation, including redness, itching, and dryness, especially in the initial stages of treatment.
- Other Likely Diagnoses:
- Allergic Contact Dermatitis: Although less common than irritant contact dermatitis, some individuals may develop an allergic reaction to tretinoin or other components of the topical formulation.
- Acne Exacerbation: Tretinoin can sometimes cause an initial flare of acne before improving the condition, which might be mistaken for a rash.
- Photosensitivity: Tretinoin can increase the skin's sensitivity to sunlight, leading to a rash-like reaction upon sun exposure.
- Do Not Miss Diagnoses:
- Erythema Multiforme: A severe skin condition that could be triggered by an allergic reaction to tretinoin, characterized by target lesions.
- Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: Although extremely rare, these are life-threatening conditions that could be precipitated by a drug reaction, including to tretinoin.
- Rare Diagnoses:
- Psoriasis or Eczematous Reaction: In rare cases, tretinoin might exacerbate or trigger psoriasis or an eczematous reaction in predisposed individuals.
- Granulomatous Reaction: A rare inflammatory reaction that could theoretically occur in response to tretinoin.