I am a woman tracking my menstrual cycle with hormone levels (FSH, estradiol, LH, progesterone‑metabolite) from cycle days 5‑14 (estradiol peaked at 288 pg/mL on day 13, LH peaked at 45 IU/L on day 13, progesterone‑metabolite rose on day 14); did I ovulate, on which day did ovulation occur, and when should I start luteal‑phase progesterone supplementation?

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Ovulation Timing and Progesterone Supplementation

Based on your hormone pattern, you ovulated on cycle day 14, approximately 24-36 hours after your LH peak on day 13, and you should start progesterone supplementation 3 days after ovulation (cycle day 16-17).

Evidence of Ovulation

Your hormone data demonstrates a classic ovulatory pattern:

  • LH surge peaked at 45 IU/L on cycle day 13, which is the definitive trigger for ovulation 1
  • Estradiol (E1G) peaked at 288.2 pg/mL on day 13, immediately before the LH peak, which is the expected follicular phase pattern 2
  • LH remained elevated at 45 IU/L on day 14 morning, then declined to 27.9 by evening of day 14, confirming the surge was resolving 1
  • Progesterone metabolite (PDG) began rising from 3.1 on day 13 to 4.7 on day 14, indicating early corpus luteum formation 2

Ovulation typically occurs 24-36 hours after the LH surge begins, which places your ovulation on cycle day 14 1. The decline in estradiol from 288.2 to 197.8 between days 13-14 and the simultaneous rise in progesterone metabolite confirms follicle rupture occurred 2.

Timing of Progesterone Supplementation

Start progesterone supplementation on cycle day 16-17 (3 days post-ovulation):

  • The corpus luteum requires 2-3 days after ovulation to establish baseline progesterone production 2
  • Starting progesterone too early (before day 16) may interfere with natural corpus luteum development
  • Your baseline PDG of 3.2 on day 5 and the rise to 4.7 on day 14 suggests early luteal phase is beginning, but supplementation should wait until the corpus luteum is fully functional 2

Key Clinical Considerations

Common pitfalls to avoid:

  • Do not start progesterone immediately after the LH surge; the corpus luteum needs time to form 2
  • Your progesterone metabolite of 4.7 on day 14 is still near baseline (3.2), which is expected immediately post-ovulation 2
  • The fertile window extends from 5 days before ovulation through the day of ovulation itself, so days 9-14 were your fertile days 3, 2

Important context about cycle variability:

  • While your LH peak occurred on day 13, ovulation timing can vary considerably even in regular cycles 4, 2
  • Only 30% of women have their fertile window entirely between days 10-17, despite this being the commonly cited range 2
  • Your FSH fluctuations (8.7 on day 5,12.2 on day 7, then 2.4 on day 9) are within normal variability for follicular development 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The probability of conception on different days of the cycle with respect to ovulation: an overview.

Advances in contraception : the official journal of the Society for the Advancement of Contraception, 1997

Research

Can apps and calendar methods predict ovulation with accuracy?

Current medical research and opinion, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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