Is a serum vitamin B12 (cobalamin) level of 349 pg/mL normal in an asymptomatic adult, and what management is recommended?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 13, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

Can an 81-year-old patient with a confirmed vitamin B12 deficiency receive another vitamin B12 injection 6 days after the initial injection, or should they wait exactly 1 week?
What is an acceptable oral vitamin B12 (cobalamin) supplement alternative to intramuscular injections for a patient with severely low vitamin B12 levels, particularly those with malabsorption or pernicious anemia?
What is the recommended treatment for a 41-year-old with a borderline Vitamin B12 deficiency?
What is the recommended treatment and management plan for a patient with a borderline Vitamin B12 level?
My serum vitamin B12 level is 1600 pg/mL; does this indicate a deficiency requiring treatment or what is the appropriate management?
Given iron studies showing total iron‑binding capacity 409 µg/dL, unsaturated iron‑binding capacity 355 µg/dL, serum iron 54 µg/dL, and iron saturation 13 %, what is the most likely diagnosis and what are the appropriate next steps in management?
What is the recommended folic acid dose for a patient receiving phenytoin?
What is the preferred first‑line regimen for treating a confirmed or suspected Ureaplasma infection in a patient allergic to doxycycline?
In a stable 29-year-old woman with depression and alcohol use disorder who is drowsy, has slurred speech, smells of alcohol, and reports occasional marijuana cravings, what is the most appropriate next step: urine drug screen, liver function tests, thyroid‑stimulating hormone level, or head computed tomography?
In an asymptomatic adult with a blood ammonia concentration <9 µmol/L, what is the appropriate next step?
What is the most appropriate next step in managing a child with atopic dermatitis that has not improved with emollients and low‑ to medium‑potency topical corticosteroids?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.