In a patient on a GLP‑1 receptor agonist who is scheduled for a fasting or anesthetic procedure or who develops marked nausea/vomiting, how long should the medication be withheld, how should the dose‑escalation schedule be adjusted, and what short‑acting alternatives can be used for rapid glucose lowering?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board

Educational purpose only • Exercise caution as content is pending human review

Article Review Status

Submitted

Under Review

Approved

Last updated: February 13, 2026 • View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

What are the risks and side effects of Glucagon-like peptide-1 (GLP-1) receptor agonists?

What is the duration that GLP-1 (Glucagon-like peptide-1) receptor agonists have been available on the market?

In a 38-year-old male smoker with type 2 diabetes mellitus with elevated HbA1c despite metformin, a sodium‑glucose cotransporter‑2 inhibitor, a dipeptidyl peptidase‑4 inhibitor and basal insulin; uncontrolled hypertension on perindopril; markedly elevated low‑density lipoprotein cholesterol despite statin; class II obesity; impaired renal function; and osteoarthritis, which of the following is the most appropriate next treatment: bariatric surgery, glucagon‑like peptide‑1 receptor agonist, phentermine, or very‑low‑calorie diet?

Is it okay to add glipizide (a sulfonylurea) 5 mg to a 48-year-old patient with type 2 diabetes on Lantus (insulin glargine) 23 units, 1:10 carb ratio, and Farxiga (dapagliflozin) 10 mg, who does not want to start mealtime insulin or GLP-1 receptor agonists?

Does a patient with pre-diabetes and a BMI of 25.5 qualify for a GLP-1 receptor agonist?

How should Mycobacterium avium complex infection be treated in immunocompromised patients such as those with advanced HIV infection (CD4 count < 50 cells/µL), organ transplant recipients, or chronic lung disease?

When should an echocardiogram be ordered for a heart murmur?

Which medications are known to cause macrocytic anemia?

After increasing haloperidol to 25 mg daily, trazodone to 100 mg, and valproate (Depakote) to 750 mg, I now have lip tremor, restless hands, and inability to stay still—how should this be managed?

What is the recommended initial management and antibiotic regimen for an adult with aspiration pneumonia, including considerations for elderly patients, dysphagia, impaired consciousness, and β‑lactam allergy?

In a 47-year-old woman with well-controlled hypertension on valsartan-hydrochlorothiazide and amlodipine, normal renal function and urine albumin/creatinine ratio, but a random urine glucose of 101 mg/dL, what is the appropriate next step in management?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.