From the Research
Kallikrein is pronounced as "kuh-LIK-ree-in" with the emphasis on the second syllable. The "k" at the beginning is pronounced like a hard "k" sound, the "a" is a short "uh" sound, the "ll" is pronounced as a single "l", the "i" is a short "i" as in "sit", the "kre" has a long "e" sound, and the final "in" is pronounced like "in" in "begin." This pronunciation applies to the family of serine proteases known as kallikreins, which are enzymes found in tissues and bodily fluids, as discussed in various studies 1, 2, 3, 4, 5. These enzymes play important roles in various physiological processes including blood pressure regulation, inflammation, and cancer progression, as noted in research on their role in the cardiovascular system 3 and their potential as biomarkers for cancer diagnosis and prognosis 1. The term comes from scientific nomenclature, which is why its pronunciation might not follow typical English language patterns. When discussing these enzymes in medical or scientific contexts, using the correct pronunciation helps ensure clear communication among healthcare professionals and researchers. Key aspects of kallikreins include their involvement in the kallikrein-kinin system, which has been implicated in several physiopathological effects in mammals, including the regulation of vascular smooth muscle tone and arterial blood pressure 3. Understanding the correct pronunciation of kallikrein is essential for effective communication in medical and scientific discussions about these enzymes and their roles in human health and disease.