From the FDA Drug Label
WARNING Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately. The FDA drug label does not answer the question about iron glycinate.
From the Research
Iron glycinate is not the preferred form of iron supplementation due to its lower efficacy compared to ferrous sulfate in treating iron deficiency anemia, as shown in a study published in 2008 1.
Key Points to Consider
- The study compared ferrous sulfate and ferrous glycinate chelate in 18 gastrectomized patients with iron deficiency anemia and found that patients treated with ferrous sulfate had better results in hematologic laboratory parameters than those who used ferrous glycinate chelate.
- However, other studies have shown that ferrous bisglycinate, a similar form of iron supplementation, has high bioavailability and is effective in treating iron deficiency anemia in infants and young children 2 and in preventing iron deficiency and anemia during pregnancy 3.
- When considering iron supplementation, it is essential to choose a form that is well-tolerated and easily absorbed by the body, and to take it with food to minimize stomach upset.
- Additionally, taking iron supplements with vitamin C-rich foods or a vitamin C supplement can enhance absorption, while avoiding consumption with calcium-rich foods, tea, coffee, or dairy products can help prevent interference with absorption.
Recommendations for Iron Supplementation
- For those needing iron supplementation, ferrous sulfate is recommended at doses of 30-60 mg of elemental iron daily, typically divided into 1-2 doses taken with food to minimize stomach upset.
- However, for individuals who experience digestive discomfort with traditional iron supplements like ferrous sulfate, ferrous bisglycinate may be a suitable alternative, as it has been shown to be well-tolerated and effective in certain populations 2, 3.
- It is crucial to consult with a healthcare professional to determine the best course of treatment for iron deficiency anemia, as they can recommend the most appropriate form and dosage of iron supplementation based on individual needs and health status.