What is the effect of Tetrahydrocannabinol (THC) and cannabis (marijuana) on female libido?

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Last updated: April 22, 2025View editorial policy

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From the Guidelines

THC and marijuana should not be recommended for increased libido in women due to the lack of strong evidence supporting its effectiveness and the potential risks associated with its use, including psychiatric and cardiovascular side effects, as well as the risk of cannabis use disorder 1. When considering the use of THC and marijuana for increased libido, it is essential to weigh the potential benefits against the potential risks. While some women report that THC and marijuana can enhance sexual experiences, the evidence is mixed, and the risks associated with its use cannot be ignored.

  • The potential risks of THC and marijuana use include psychiatric side effects, such as depressive disorders and anxiety, as well as cardiovascular side effects, such as arrhythmias and orthostatic hypotension 1.
  • Additionally, the use of THC and marijuana can lead to cannabis use disorder, which is associated with clinically significant impairment or distress, including using more cannabis than expected and difficulty in cutting back on use 1.
  • The evidence for the effectiveness of THC and marijuana in increasing libido is limited, and more research is needed to fully understand its potential benefits and risks.
  • In light of the potential risks and limited evidence, it is recommended that women consult with their healthcare providers before using cannabis, especially if taking other medications or planning pregnancy.
  • Alternative approaches to addressing low libido, such as counseling, lifestyle changes, and other evidence-based treatments, should be considered before turning to THC and marijuana.
  • It is crucial to prioritize the potential risks and benefits of THC and marijuana use and to make informed decisions based on the strongest available evidence, which currently does not support its use for increased libido in women 1.

From the Research

THC and Marijuana Use for Increased Libido in Women

  • There is no direct evidence in the provided studies to support the use of THC and marijuana for increased libido in women 2, 3, 4, 5, 6.
  • The studies primarily focus on hormone replacement therapy (HRT) for menopausal symptoms and its benefits and risks 2, 3, 4, 6.
  • One study discusses the use of tetrahydrocannabinol (THC) and cannabidiol (CBD) medicines for chronic pain and mental health conditions, but does not mention libido or sexual health 5.
  • The current evidence does not provide a clear answer to the question of using THC and marijuana for increased libido in women, and more research is needed to explore this topic.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Counseling on hormone replacement therapy: the real risks and benefits.

Current opinion in obstetrics & gynecology, 2023

Research

Hormone replacement therapy - where are we now?

Climacteric : the journal of the International Menopause Society, 2021

Research

Hormone replacement therapy - Current recommendations.

Best practice & research. Clinical obstetrics & gynaecology, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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