What is the appropriate next management for a 34‑year‑old woman with cervical cancer receiving cisplatin and paclitaxel who developed acute pyelonephritis, had a double‑J ureteral stent placed four days ago, and remains febrile with persistent leukocytosis despite four days of ceftriaxone therapy?

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Last updated: February 15, 2026 • View editorial policy

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What is the likely diagnosis and recommended management for a 34-year-old woman with cervical cancer on cisplatin‑paclitaxel chemotherapy who has acute pyelonephritis, persistent leukocytosis after four days of ceftriaxone, is afebrile for more than 48 hours, has stable blood pressure, and ultrasound shows moderate hydronephrosis with bilateral double‑J stents?

What is the appropriate diagnostic work‑up and management for a 34‑year‑old woman with cervical cancer treated with cisplatin and paclitaxel who presents with acute pyelonephritis, had a double‑J ureteral stent placed four days ago, and now has persistent leukocytosis with neutrophilia despite four days of ceftriaxone therapy?

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