What is the recommended dosage for Glutathione injections?

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Last updated: April 23, 2025 • View editorial policy

From the Research

Glutathione shots dosage should be individualized, but a common range is 600-1200 mg per dose, administered 1-3 times per week, with the most recent and highest quality study suggesting that oral supplementation can be effective in increasing body stores of glutathione 1. When considering glutathione injections, it's essential to prioritize the individual's needs and treatment goals.

  • For general wellness and antioxidant support, starting with 600 mg weekly is common, while higher doses of 1200 mg 2-3 times weekly may be used for specific conditions like skin lightening or detoxification support.
  • These injections should be administered intramuscularly by a healthcare professional, as improper technique can lead to complications.
  • Before starting glutathione injections, patients should undergo a medical evaluation to ensure they have no contraindications such as asthma (as glutathione may worsen symptoms in some asthmatics) or allergies to the components.
  • Side effects are generally mild but may include rash, nausea, or injection site reactions.
  • Glutathione works as a master antioxidant in the body, neutralizing free radicals and supporting detoxification pathways in the liver.
  • The injectable form is used because oral glutathione is poorly absorbed in the digestive tract, although recent studies suggest that oral supplementation with liposomal glutathione can be effective in elevating body stores of glutathione 1.
  • Treatment duration varies based on goals, ranging from a few weeks to several months, with maintenance doses often recommended after the initial treatment period. It's crucial to note that the most recent and highest quality study on oral glutathione supplementation 1 found that daily consumption of glutathione supplements was effective at increasing body compartment stores of glutathione, which may inform the decision on dosage and administration route.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.