What laboratory tests should be collected in a 15-year-old female?

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Last updated: April 23, 2025View editorial policy

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From the Guidelines

For a 15-year-old female, the recommended laboratory tests should include a complete blood count (CBC), comprehensive metabolic panel, lipid panel, thyroid function tests, urinalysis, and hemoglobin A1C, as well as screening for sexually transmitted infections if sexually active, as supported by 1 and 1.

Laboratory Tests

The following laboratory tests are recommended:

  • Complete blood count (CBC) to assess for anemia, white blood cell count, and platelet levels
  • Comprehensive metabolic panel to evaluate kidney and liver function, electrolytes, and glucose levels
  • Lipid panel to screen for cholesterol abnormalities
  • Thyroid function tests including TSH to check for thyroid disorders
  • Urinalysis to screen for urinary tract infections or kidney issues
  • Hemoglobin A1C to screen for diabetes

Sexually Transmitted Infection Screening

Sexually active adolescents should be screened for sexually transmitted infections, including:

  • Chlamydia
  • Gonorrhea
  • HIV As recommended by 1 and 1, screening for these infections is crucial in preventing long-term complications and promoting public health.

Additional Tests

Additional tests may be considered based on the patient's medical history, family history, presenting symptoms, and risk factors, such as:

  • Iron studies to evaluate for iron deficiency anemia
  • Vitamin D levels, especially in those with limited sun exposure or dietary restrictions These tests provide a comprehensive baseline assessment of the adolescent's health status and can identify common conditions that may emerge during puberty and adolescence, as supported by 1 and 1.

From the Research

Laboratory Tests for a 15-Year-Old Female

The following laboratory tests are relevant for a 15-year-old female:

  • Complete Blood Count (CBC) with differential count and reticulocyte count, as it provides valuable information for diagnosing blood disorders 2
  • Hemoglobin and hematocrit levels, which should be part of a baseline hematology evaluation starting at age 12 months, or younger if clinically indicated 2

Rationale for Laboratory Tests

The rationale for collecting these laboratory tests is to:

  • Narrow the differential diagnosis and tailor the subsequent evaluation 2
  • Identify possible diagnoses before consulting a specialist 2
  • Inform the plan of care and produce the best patient outcomes 3

Key Considerations

Key considerations for interpreting laboratory test results include:

  • The interpretation of CBC results requires practice and skill 2
  • Clinicians can learn to identify possible diagnoses using a step-by-step approach for CBC interpretation 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

CE: Back to Basics: The Complete Blood Count.

The American journal of nursing, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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