Inpatient Epic Dot Phrase for COPD Exacerbation
Assessment and Diagnosis
.COPDEXACERB
Chief Complaint: Acute exacerbation of COPD
HPI: Patient with known COPD presenting with acute worsening of respiratory symptoms. Cardinal symptoms present:
- Increased dyspnea
- Increased sputum volume
- Increased sputum purulence
Severity Classification: 1
- Mild (outpatient management with SABAs only)
- Moderate (requires SABAs + antibiotics/corticosteroids)
- Severe (requires hospitalization ± acute respiratory failure)
Triggers assessed:
- Recent respiratory infection
- Medication non-adherence
- Environmental exposures
- Smoking status: ___ pack-years
Exacerbation frequency past year: ___ episodes 2
Initial Management
- Target SpO2: 88-92% using Venturi mask (24-28% FiO2) or nasal cannula (1-2 L/min)
- ABG obtained within 60 minutes of oxygen initiation
- Repeat ABG at 30-60 minutes if pH <7.35 or PaCO2 >45 mmHg
- Albuterol 2.5-5 mg + Ipratropium 0.25-0.5 mg via nebulizer q4-6h
- Nebulizers powered with compressed air (not oxygen) if hypercapnic
- Continue until clinical improvement (typically 24-48 hours)
Systemic Corticosteroids: 2, 1
- Prednisone 40 mg PO daily x 5 days (started immediately)
- Oral route preferred unless unable to tolerate PO
- Do NOT extend beyond 5-7 days without separate indication
Antibiotic Therapy (if indicated): 2, 1 Criteria: Increased sputum purulence PLUS (increased dyspnea OR increased sputum volume)
- Amoxicillin-clavulanate 875/125 mg PO BID x 5-7 days (first-line)
- Doxycycline 100 mg PO BID x 5-7 days (alternative)
- Azithromycin 500 mg day 1, then 250 mg daily x 4 days (alternative)
Respiratory Support
NIV Indications: 2, 1 Initiate immediately if:
- pH <7.35 with PaCO2 >45 mmHg persisting >30 minutes after initial therapy
- Persistent hypoxemia despite oxygen
- Severe dyspnea with respiratory muscle fatigue
NIV Contraindications: 2
- Altered mental status/inability to protect airway
- Large volume secretions
- Hemodynamic instability
- Recent facial/upper airway surgery
Monitoring
Vital Signs: q4h initially, then per nursing protocol ABG: Within 1 hour of oxygen initiation, repeat PRN based on clinical status 2 Chest X-ray: To exclude pneumonia, pneumothorax, pulmonary edema 2 ECG: If HR <60 or >110, or cardiac symptoms present 2 Labs: CBC, CMP (assess electrolytes, renal function, glucose) 2
Discharge Planning
- Continue/optimize long-acting bronchodilators (LAMA/LABA/ICS) before discharge
- Do NOT step down from triple therapy during or immediately after exacerbation
- Verify inhaler technique at discharge
Pulmonary Rehabilitation: 2, 1
- Schedule within 3 weeks after discharge (NOT during hospitalization)
- Reduces readmissions and improves quality of life
Follow-up: 2
- Outpatient appointment within 3-7 days
- Smoking cessation counseling if applicable
- Review exacerbation prevention strategies
Medications to AVOID
- Methylxanthines (theophylline/aminophylline): Increased side effects without benefit 2, 1
- Chest physiotherapy: No evidence of benefit in acute exacerbations 2
- High-flow oxygen (>28% FiO2) without ABG monitoring: Worsens hypercapnic respiratory failure 2
Plan: Admit to [floor/ICU]. Continue above management. Reassess in 30-60 minutes for clinical response. 1, 2