Can you create an inpatient Epic dot phrase for an acute COPD exacerbation?

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Last updated: February 15, 2026View editorial policy

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Inpatient Epic Dot Phrase for COPD Exacerbation

Assessment and Diagnosis

.COPDEXACERB

Chief Complaint: Acute exacerbation of COPD

HPI: Patient with known COPD presenting with acute worsening of respiratory symptoms. Cardinal symptoms present:

  • Increased dyspnea
  • Increased sputum volume
  • Increased sputum purulence

Severity Classification: 1

  • Mild (outpatient management with SABAs only)
  • Moderate (requires SABAs + antibiotics/corticosteroids)
  • Severe (requires hospitalization ± acute respiratory failure)

Triggers assessed:

  • Recent respiratory infection
  • Medication non-adherence
  • Environmental exposures
  • Smoking status: ___ pack-years

Exacerbation frequency past year: ___ episodes 2


Initial Management

Oxygen Therapy: 2, 1

  • Target SpO2: 88-92% using Venturi mask (24-28% FiO2) or nasal cannula (1-2 L/min)
  • ABG obtained within 60 minutes of oxygen initiation
  • Repeat ABG at 30-60 minutes if pH <7.35 or PaCO2 >45 mmHg

Bronchodilator Therapy: 2, 1

  • Albuterol 2.5-5 mg + Ipratropium 0.25-0.5 mg via nebulizer q4-6h
  • Nebulizers powered with compressed air (not oxygen) if hypercapnic
  • Continue until clinical improvement (typically 24-48 hours)

Systemic Corticosteroids: 2, 1

  • Prednisone 40 mg PO daily x 5 days (started immediately)
  • Oral route preferred unless unable to tolerate PO
  • Do NOT extend beyond 5-7 days without separate indication

Antibiotic Therapy (if indicated): 2, 1 Criteria: Increased sputum purulence PLUS (increased dyspnea OR increased sputum volume)

  • Amoxicillin-clavulanate 875/125 mg PO BID x 5-7 days (first-line)
  • Doxycycline 100 mg PO BID x 5-7 days (alternative)
  • Azithromycin 500 mg day 1, then 250 mg daily x 4 days (alternative)

Respiratory Support

NIV Indications: 2, 1 Initiate immediately if:

  • pH <7.35 with PaCO2 >45 mmHg persisting >30 minutes after initial therapy
  • Persistent hypoxemia despite oxygen
  • Severe dyspnea with respiratory muscle fatigue

NIV Contraindications: 2

  • Altered mental status/inability to protect airway
  • Large volume secretions
  • Hemodynamic instability
  • Recent facial/upper airway surgery

Monitoring

Vital Signs: q4h initially, then per nursing protocol ABG: Within 1 hour of oxygen initiation, repeat PRN based on clinical status 2 Chest X-ray: To exclude pneumonia, pneumothorax, pulmonary edema 2 ECG: If HR <60 or >110, or cardiac symptoms present 2 Labs: CBC, CMP (assess electrolytes, renal function, glucose) 2


Discharge Planning

Maintenance Therapy: 2, 1

  • Continue/optimize long-acting bronchodilators (LAMA/LABA/ICS) before discharge
  • Do NOT step down from triple therapy during or immediately after exacerbation
  • Verify inhaler technique at discharge

Pulmonary Rehabilitation: 2, 1

  • Schedule within 3 weeks after discharge (NOT during hospitalization)
  • Reduces readmissions and improves quality of life

Follow-up: 2

  • Outpatient appointment within 3-7 days
  • Smoking cessation counseling if applicable
  • Review exacerbation prevention strategies

Medications to AVOID

  • Methylxanthines (theophylline/aminophylline): Increased side effects without benefit 2, 1
  • Chest physiotherapy: No evidence of benefit in acute exacerbations 2
  • High-flow oxygen (>28% FiO2) without ABG monitoring: Worsens hypercapnic respiratory failure 2

Plan: Admit to [floor/ICU]. Continue above management. Reassess in 30-60 minutes for clinical response. 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

COPD Exacerbation Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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