From the Research
Matcha tea should be consumed with caution if you are taking apixaban due to potential interactions, and it is recommended to maintain consistent, moderate matcha consumption to minimize risks. While occasional consumption of matcha is likely safe, regular or high intake could potentially affect apixaban's effectiveness. Matcha contains vitamin K, which can counteract anticoagulant medications, though in lower amounts than foods like kale or spinach. Additionally, matcha contains catechins that may inhibit certain enzymes involved in metabolizing apixaban, potentially increasing drug levels and bleeding risk 1.
Key Considerations
- The most recent and highest quality study on apixaban interactions is from 2023, which found that apixaban is effective and safe in patients with venous thromboembolism, including those with risk factors for bleeding or recurrences 2.
- A 2020 systematic review of drug interactions with apixaban found that the most reported adverse drug reactions were related to hemorrhage or thrombosis, mostly through pharmacodynamic interactions 1.
- A 2015 meta-analysis found that apixaban is associated with a lower risk of bleeding than vitamin K antagonists, providing some reassurance regarding its safety 3.
Recommendations
- If you take apixaban, it's best to maintain consistent, moderate matcha consumption rather than dramatically changing your intake patterns.
- Any significant changes in diet, including starting or stopping regular matcha consumption, should be discussed with your healthcare provider.
- Monitor for unusual bleeding or bruising, and inform your doctor about all dietary supplements and beverages you regularly consume.
- Your doctor may need to adjust your apixaban dosage or recommend specific timing between your medication and matcha consumption to minimize potential interactions.