What is the term for chest pain associated with anaphylaxis?

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Last updated: April 23, 2025View editorial policy

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From the Guidelines

The term for chest pain with anaphylaxis is not explicitly defined in the provided evidence, but based on the symptoms of anaphylaxis, it can be related to the cardiovascular system symptoms described, such as weak pulse, dizziness, or passing out, which may be associated with chest pain or discomfort 1. When considering the symptoms of anaphylaxis, it's crucial to recognize that they can affect multiple systems, including the cardiovascular system, which may lead to chest pain or discomfort.

  • The symptoms of anaphylaxis include:
    • Mouth: itching; swelling of lips and/or tongue
    • Throat: itching; tightness/closure; hoarseness
    • Skin: itching; hives; redness; swelling
    • Gut: vomiting; diarrhea; cramps
    • Lung: shortness of breath; cough; wheeze
    • Heart: weak pulse; dizziness; passing out Given the potential for severe and life-threatening symptoms, it's essential to act quickly and treat anaphylaxis with epinephrine, which can help alleviate symptoms, including those related to the cardiovascular system, such as chest pain or discomfort, by improving cardiac output and reducing the allergic response 1. In clinical practice, if a patient experiences chest pain during anaphylaxis, it should be considered a severe symptom requiring immediate treatment with epinephrine (0.3-0.5mg intramuscularly for adults, 0.15mg for small children) to address both the anaphylaxis and the potential coronary effects.

From the Research

Definition and Symptoms

  • The term for chest pain associated with anaphylaxis is not explicitly defined in the provided studies 2, 3, 4, 5, 6.
  • Anaphylaxis is a recognized cause of death in all ages, which requires prompt recognition and treatment 3.
  • Symptoms of anaphylaxis can include bronchospasm, airway obstruction, hypotension, and shock 2, 3, 6.

Treatment and Management

  • Epinephrine is the first-line treatment for anaphylaxis and is recognized as the only medication documented to prevent hospitalizations, hypoxic sequelae, and fatalities 2, 3, 4, 6.
  • Antihistamines and glucocorticosteroids should not be prescribed in place of epinephrine, but may be used as second-line or third-line treatment 2, 3, 4, 5, 6.
  • β-adrenergic agonists by inhalation are indicated for bronchospasm associated with anaphylaxis despite optimal epinephrine treatment 2.

Specifics of Chest Pain in Anaphylaxis

  • There is no specific information available in the provided studies regarding the term for chest pain with anaphylaxis 2, 3, 4, 5, 6.
  • However, it is known that anaphylaxis can cause cardiac symptoms, including hypotension and arrhythmias 3, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Management of Anaphylaxis.

Immunology and allergy clinics of North America, 2022

Research

Therapeutic approach of anaphylaxis.

Current opinion in allergy and clinical immunology, 2019

Research

Managing anaphylaxis: Epinephrine, antihistamines, and corticosteroids: More than 10 years of Cross-Canada Anaphylaxis REgistry data.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2023

Research

Corticosteroids in management of anaphylaxis; a systematic review of evidence.

European annals of allergy and clinical immunology, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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