From the FDA Drug Label
Principal Display Panel TopCare Miconazorb AF ANTIFUNGAL POWDER MICONAZOLE NITRATE 2%/ ANTIFUNGAL Cures Most Athlete's Foot, Jock Itch & Ringworm Active ingredient Miconazole nitrate 2% The most effective topical antifungal for tinea corporis is miconazole.
- Miconazole is effective in curing ringworm, which is another name for tinea corporis, as stated in the drug label 1.
- The active ingredient in the drug is Miconazole nitrate 2% 1.
From the Research
Terbinafine cream is the most effective topical antifungal for tinea corporis, with a mycological cure rate of over 80% when applied once or twice daily for 1-2 weeks. The treatment of tinea corporis typically involves the use of topical antifungal agents, and terbinafine has been shown to be highly effective in achieving mycological cure and clinical improvement 2, 3.
Key Considerations
- Terbinafine is preferred over other topical antifungals due to its fungicidal properties, which lead to faster resolution and lower recurrence rates 2.
- The recommended dosage is 1% terbinafine cream applied once or twice daily for 1-2 weeks 3.
- Other effective options include clotrimazole, miconazole, or ketoconazole creams, which should be applied twice daily for 2-4 weeks 4.
- For optimal results, it is essential to continue treatment for at least one week after symptoms resolve, keep the affected area clean and dry, avoid sharing personal items, and wash clothes and bedding in hot water 4.
Recent Studies
A recent study published in 2023 compared the efficacy and safety of 250 mg versus 500 mg oral terbinafine in the treatment of tinea corporis and cruris, and found that the higher dose did not have any additional benefit 5. Another study published in 2013 compared the efficacy and safety of terbinafine hydrochloride 1% cream and sertaconazole nitrate 2% cream in tinea corporis and tinea cruris, and found that both treatments had similar efficacy and safety profiles 6.
Clinical Implications
In clinical practice, terbinafine cream is a valuable treatment option for tinea corporis due to its high efficacy, safety, and convenience of use. Patients should be advised to apply the cream as directed and to maintain good hygiene practices to prevent the spread of the infection. If the infection is extensive, does not improve after two weeks of treatment, or recurs frequently, oral antifungal therapy may be necessary 5.