From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Armodafinil is generally well-tolerated, but it can cause several genitourinary symptoms as side effects, including urinary retention, difficulty urinating, and increased urinary frequency, as well as decreased libido or sexual dysfunction, as reported in various studies 1, 2, 3, 4.
Genitourinary Symptoms
The genitourinary symptoms associated with armodafinil are primarily related to its effects on neurotransmitters in the brain, particularly dopamine and norepinephrine, which can influence urinary tract function and sexual response.
- Urinary retention
- Difficulty urinating
- Increased urinary frequency
- Decreased libido
- Sexual dysfunction
Management of Genitourinary Symptoms
If you experience these symptoms while taking armodafinil, it's essential to stay hydrated but avoid excessive fluid intake close to bedtime. Most genitourinary side effects are mild and temporary, often resolving as your body adjusts to the medication. However, if you experience severe symptoms like painful urination, inability to urinate, or significant sexual dysfunction, you should contact your healthcare provider promptly. They may recommend adjusting your dosage (typically available as 150mg or 250mg tablets) or switching to an alternative medication, as suggested by studies 3, 4.
Importance of Medical Guidance
Never stop taking armodafinil suddenly without medical guidance, as this can lead to withdrawal symptoms. The most recent study 5 suggests that armodafinil is generally well-tolerated and safe, but it's crucial to monitor its effects and adjust the treatment plan as needed to minimize the risk of genitourinary symptoms and other adverse events.