What are the symptoms of mitral valve stenosis (Mitral Valve Stenosis)?

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Last updated: April 23, 2025View editorial policy

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From the Guidelines

Mitral valve stenosis typically presents with symptoms such as shortness of breath, fatigue, and heart palpitations due to the narrowing of the mitral valve, which restricts blood flow from the left atrium to the left ventricle 1.

Common Symptoms

  • Shortness of breath (dyspnea), especially during physical activity or when lying flat (orthopnea)
  • Fatigue
  • Heart palpitations
  • Chest discomfort

Advanced Symptoms

  • Hemoptysis (coughing up blood)
  • Hoarseness due to compression of the recurrent laryngeal nerve by an enlarged left atrium
  • Signs of right heart failure such as peripheral edema and ascites
  • Atrial fibrillation, which can cause irregular heartbeats and increase the risk of blood clots and stroke

Disease Progression

The restricted blood flow through the stenotic valve causes increased pressure in the left atrium, which backs up into the lungs, causing pulmonary congestion and the characteristic breathing difficulties. Early symptoms may only appear during exertion when the heart needs to pump more blood, while advanced stenosis can cause symptoms even at rest.

Importance of Medical Evaluation

If you experience these symptoms, especially progressive shortness of breath, immediate medical evaluation is essential for proper diagnosis and treatment, as indicated by the 2017 ESC/EACTS guidelines for the management of valvular heart disease 1.

From the Research

Symptoms of Mitral Valve Stenosis

The symptoms of mitral valve stenosis can vary depending on the severity of the condition. Some common symptoms include:

  • Shortness of breath or difficulty breathing, especially during physical activity or when lying down
  • Fatigue or weakness
  • Palpitations or irregular heartbeat
  • Coughing or wheezing
  • Swelling in the legs or feet

Causes and Risk Factors

Mitral valve stenosis is often caused by rheumatic heart disease, which is a complication of rheumatic fever 2. Other risk factors include:

  • Age: Mitral valve stenosis is more common in older adults
  • Sex: Women are more likely to develop mitral valve stenosis than men
  • History of heart disease: People with a history of heart disease are more likely to develop mitral valve stenosis

Treatment Options

Treatment for mitral valve stenosis depends on the severity of the condition. Some treatment options include:

  • Medications: Such as diuretics, beta blockers, and anticoagulants to control symptoms and prevent complications 3
  • Percutaneous balloon mitral valvuloplasty: A minimally invasive procedure to widen the mitral valve 2
  • Surgery: To repair or replace the mitral valve

Management of Atrial Fibrillation

Atrial fibrillation is a common complication of mitral valve stenosis. Management of atrial fibrillation includes:

  • Anticoagulation therapy: To prevent stroke and other complications 3
  • Rate control: To control the heart rate and prevent symptoms 4
  • Rhythm control: To restore a normal heart rhythm 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Mitral Valve Disease: a Comprehensive Review.

Current cardiology reports, 2017

Research

Anticoagulation in Atrial Fibrillation Associated with Mitral Stenosis.

Cardiovascular & hematological agents in medicinal chemistry, 2022

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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