What are the evidence‑based guideline‑recommended first‑line and second‑line treatment options for hypertension, type 2 diabetes mellitus, and mild‑moderate depression, and how should therapy be individualized based on patient age, comorbidities, current medications, functional status, and treatment goals?

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Last updated: February 16, 2026 • View editorial policy

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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