From the Research
The Lyme C6 antigen test is a valuable diagnostic tool for detecting Lyme disease in dogs, and treatment typically involves a 28-30 day course of antibiotics, most commonly doxycycline (10 mg/kg orally twice daily), as recommended by the most recent consensus statement 1. The test specifically measures antibodies against the C6 peptide, which is part of the VlsE protein unique to Borrelia burgdorferi, the bacterium causing Lyme disease. A positive C6 test indicates active or recent infection, not just exposure or vaccination. Some key points to consider when interpreting the results of the C6 test include:
- The test can be used to monitor treatment success by measuring declining antibody levels after therapy, with follow-up testing typically recommended 6 months after treatment completion.
- Prevention remains crucial through regular tick checks, tick preventatives, and vaccination in endemic areas.
- The C6 test is particularly useful because it can help identify dogs that are at risk of developing Lyme disease, allowing for early intervention and treatment.
- It's also important to note that the C6 test is not foolproof, and false-positive and false-negative results can occur, as discussed in earlier studies 2. Beyond treatment, it's essential to have your veterinarian perform additional testing to check for kidney damage or other complications, as Lyme disease can affect multiple organ systems. Some of the key considerations for treatment and prevention include:
- The use of doxycycline as the first-line treatment for Lyme disease in dogs, as recommended by the consensus statement 1.
- The importance of regular tick checks and the use of tick preventatives to reduce the risk of transmission.
- The potential benefits and risks of vaccination, as discussed in earlier studies 3, 2.