What is the cause of swollen and tender nostrils (nares)?

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Last updated: April 23, 2025View editorial policy

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Differential Diagnosis for Swollen Tender Nares

Single Most Likely Diagnosis

  • Acute Rhinitis (Common Cold): This is the most common cause of swollen and tender nares, often resulting from viral infections that lead to inflammation of the nasal mucosa.

Other Likely Diagnoses

  • Allergic Rhinitis: Similar to the common cold but triggered by allergens, leading to nasal congestion, swelling, and tenderness.
  • Nasal Furuncle or Carbuncle: A bacterial infection of the nasal vestibule, which can cause localized pain, swelling, and tenderness.
  • Nasal Septal Hematoma: A collection of blood in the nasal septum, often due to trauma, which can cause swelling and tenderness.

Do Not Miss Diagnoses

  • Necrotizing Fasciitis: A rare but life-threatening bacterial infection that can start in the nasal area and spread rapidly, requiring immediate medical attention.
  • Malignancy (e.g., Nasal Cavity or Sinus Cancer): Although rare, cancers in this area can present with non-specific symptoms like swelling and tenderness of the nares.
  • Invasive Fungal Sinusitis: Especially in immunocompromised patients, this can be a deadly condition if not promptly diagnosed and treated.

Rare Diagnoses

  • Granulomatosis with Polyangiitis (GPA): A form of vasculitis that can affect the nasal passages, leading to swelling, tenderness, and potentially destructive lesions.
  • Sarcoidosis: A systemic disease that can cause granulomatous inflammation in the nasal mucosa, leading to swelling and tenderness.
  • Relapsing Polychondritis: An autoimmune disorder that can cause inflammation and destruction of cartilaginous structures, including the nose, leading to swelling and tenderness.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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