BMI Calculation and Classification
For an adult with height 170 cm and weight 92.5 kg, the BMI is 32.0 kg/m², which classifies as Class I obesity, and first-line management should be a comprehensive lifestyle intervention for 6-12 months targeting a 5-10% weight loss through caloric reduction of 500-750 kcal/day, at least 150 minutes weekly of moderate-intensity physical activity, and behavioral therapy with at least 14 sessions over 6 months. 1, 2
BMI Calculation
- BMI = weight (kg) / height (m)² = 92.5 / (1.70)² = 32.0 kg/m² 1, 3
- This falls into Class I obesity (BMI 30-34.9 kg/m²) according to WHO classification 1, 3
Risk Assessment Required Before Treatment
You must assess for cardiovascular risk factors and obesity-related comorbidities before initiating treatment, as their presence mandates intensive management regardless of weight loss efforts. 1, 3
Essential screening includes:
- Blood pressure measurement to identify hypertension 1, 3
- Fasting glucose and HbA1c to detect diabetes or prediabetes 3
- Lipid panel (triglycerides, HDL-C) for dyslipidemia 3
- Waist circumference: >102 cm (men) or >88 cm (women) indicates increased cardiometabolic risk 1, 3
- Assessment for sleep apnea, fatty liver disease, and other obesity-related conditions 1
- Weight history: patterns of gain/loss, previous attempts, family history of obesity 1, 3
- Medication review to identify drugs contributing to weight gain 3, 4
First-Line Treatment: Comprehensive Lifestyle Intervention
Dietary Modification
Reduce caloric intake by 500-750 kcal/day to achieve 0.5-1 kg weight loss per week, targeting an initial 5-10% body weight reduction over 6 months. 1, 2, 4
- Eliminate sugary drinks and ultra-processed foods 4
- Increase fruits and vegetables while reducing high-fat and high-sugar foods 4
- Consider portion control strategies such as meal replacements or pre-packaged meals to improve adherence 4
Physical Activity
Engage in at least 150 minutes per week of moderate-intensity aerobic activity (such as brisk walking) or 75 minutes of vigorous-intensity activity, combined with resistance training at least 2 days per week. 1, 2
- For individuals with BMI >35 kg/m², choose activities that do not burden the musculoskeletal system 1
- Reduce sedentary behaviors (TV watching, computer use) 1
- Physical activity is crucial for long-term weight maintenance but may be less effective for initial weight loss 4
Behavioral Therapy
Participate in at least 14 sessions of intensive behavioral therapy over 6 months, focusing on self-monitoring, nutrition education, and cognitive restructuring. 4
- Weekly or more frequent self-weighing for accountability 2
- Behavioral therapy typically produces 5-10% weight loss, with maximum loss occurring between 6-12 months 4
When to Add Pharmacotherapy
If weight loss is less than 5% after 3-6 months of lifestyle intervention, consider adding FDA-approved anti-obesity medications (orlistat, liraglutide, semaglutide, naltrexone/bupropion, or phentermine-topiramate). 1, 2, 4
- Pharmacotherapy is indicated for BMI ≥30 kg/m² or BMI ≥27 kg/m² with weight-related complications 1
- Medications must always be used in conjunction with lifestyle modification, never as monotherapy 4
- Continue medication only if the patient loses at least 5% of initial body weight during the first 3 months or at least 2 kg during the first 4 weeks 1
Bariatric Surgery Consideration
Bariatric surgery should be considered if BMI reaches ≥40 kg/m² or ≥35 kg/m² with obesity-related comorbidities after failure of non-surgical interventions. 1, 2
- At current BMI of 32.0 kg/m², this patient does not yet meet surgical criteria unless significant comorbidities develop 1
- Surgery requires comprehensive multidisciplinary assessment and long-term follow-up for at least 2 years 1
Long-Term Management Strategy
Obesity must be treated as a chronic disease requiring ongoing management, not a temporary condition. 1, 2
- Most weight loss occurs in the first 6 months; if weight regain occurs after stopping treatment, restart the intervention program 5
- Long-term follow-up programs (≥1 year) with regular physical activity (200-300 min/week) are essential for weight maintenance 2
- Take a daily multivitamin at bedtime if using orlistat due to fat-soluble vitamin malabsorption 5
Common Pitfalls to Avoid
- Do not rely on BMI alone for risk assessment—it does not distinguish muscle from fat or capture central adiposity patterns 3, 6
- Do not skip waist circumference measurement in patients with BMI <35 kg/m², as it provides additional cardiovascular risk information 1, 3
- Do not delay intensive management of cardiovascular risk factors (hypertension, dyslipidemia, diabetes) while pursuing weight loss 1, 3
- Do not use person-last language—say "person with obesity" rather than "obese person" 2
- Do not set unrealistic expectations—a 5-10% weight reduction produces significant clinical benefits even if it seems modest 2, 4